Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

The cellular and functional complexity of thermogenic fat

P Cohen, S Kajimura - Nature Reviews Molecular Cell Biology, 2021 - nature.com
Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy
in the form of heat. These thermogenic fat cells were originally considered to function solely …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies

J Morze, C Wittenbecher, L Schwingshackl… - Diabetes …, 2022 - Am Diabetes Assoc
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

Y Zheng, SH Ley, FB Hu - Nature reviews endocrinology, 2018 - nature.com
Globally, the number of people with diabetes mellitus has quadrupled in the past three
decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults …

Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Mediterranean diet effects on type 2 diabetes prevention, disease progression, and related mechanisms. A review

S Martín-Peláez, M Fito, O Castaner - Nutrients, 2020 - mdpi.com
The search for a quality diet has grown over the past decade. Diet is considered one of the
pillars for the prevention and progression of several diseases, among them: diabetes. Type …

[PDF][PDF] Molecular choreography of acute exercise

K Contrepois, S Wu, KJ Moneghetti, D Hornburg… - Cell, 2020 - cell.com
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system …

A longitudinal big data approach for precision health

SM Schüssler-Fiorenza Rose, K Contrepois… - Nature medicine, 2019 - nature.com
Precision health relies on the ability to assess disease risk at an individual level, detect early
preclinical conditions and initiate preventive strategies. Recent technological advances in …