Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring

F Mirabella, G Desiato, S Mancinelli, G Fossati… - Immunity, 2021 - cell.com
Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …

Magnetic resonance imaging in animal models of Alzheimer's disease amyloidosis

R Ni - International Journal of Molecular Sciences, 2021 - mdpi.com
Amyloid-beta (Aβ) plays an important role in the pathogenesis of Alzheimer's disease.
Aberrant Aβ accumulation induces neuroinflammation, cerebrovascular alterations, and …

Impact of fatty acids on brain circulation, structure and function

RAM Haast, AJ Kiliaan - Prostaglandins, Leukotrienes and Essential Fatty …, 2015 - Elsevier
The use of dietary intervention has evolved into a promising approach to prevent the onset
and progression of brain diseases. The positive relationship between intake of omega-3 …

A CNN–RNN–LSTM based amalgamation for Alzheimer's disease detection

M Dua, D Makhija, PYL Manasa, P Mishra - Journal of Medical and …, 2020 - Springer
Purpose Alzheimer's disease is a fatal brain condition that causes irreversible brain damage
and gradually depletes memory of an individual. The basic idea of the presented work in this …

[HTML][HTML] Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: a multimodal imaging investigation

AM Racine, N Adluru, AL Alexander, BT Christian… - NeuroImage: Clinical, 2014 - Elsevier
Some cognitively healthy individuals develop brain amyloid accumulation, suggestive of
incipient Alzheimer's disease (AD), but the effect of amyloid on other potentially informative …

[HTML][HTML] Altered whole-brain white matter networks in preclinical Alzheimer's disease

FU Fischer, D Wolf, A Scheurich, A Fellgiebel… - NeuroImage …, 2015 - Elsevier
Surrogates of whole-brain white matter (WM) networks reconstructed using diffusion tensor
imaging (DTI) are novel markers of structural brain connectivity. Global connectivity of …

Structural-functional connectivity deficits of neocortical circuits in the Fmr1−/y mouse model of autism

MG Haberl, V Zerbi, A Veltien, M Ginger… - Science …, 2015 - science.org
Fragile X syndrome (FXS), the most common inherited form of intellectual disability disorder
and a frequent cause of autism spectrum disorder (ASD), is characterized by a high …

Dysfunctional autism risk genes cause circuit-specific connectivity deficits with distinct developmental trajectories

V Zerbi, GD Ielacqua, M Markicevic, MG Haberl… - Cerebral …, 2018 - academic.oup.com
Autism spectrum disorders (ASD) are a set of complex neurodevelopmental disorders for
which there is currently no targeted therapeutic approach. It is thought that alterations of …

Aberrant somatosensory processing and connectivity in mice lacking Engrailed-2

G Chelini, V Zerbi, L Cimino, A Grigoli… - Journal of …, 2019 - Soc Neuroscience
Overreactivity and defensive behaviors in response to tactile stimuli are common symptoms
in autism spectrum disorder (ASD) patients. Similarly, somatosensory hypersensitivity has …

Resting-state functional connectivity changes in aging apoE4 and apoE-KO mice

V Zerbi, M Wiesmann, TL Emmerzaal… - Journal of …, 2014 - Soc Neuroscience
It is well established that the cholesterol-transporter apolipoprotein ε (APOE) genotype is
associated with the risk of developing neurodegenerative diseases. Recently, brain …