[HTML][HTML] Anti-angiogenic therapy: current challenges and future perspectives

F Lopes-Coelho, F Martins, SA Pereira… - International journal of …, 2021 - mdpi.com
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Clinical practice guideline for the management of infantile hemangiomas

DP Krowchuk, IJ Frieden, AJ Mancini, DH Darrow… - …, 2019 - publications.aap.org
This is the first clinical practice guideline (CPG) from the American Academy of Pediatrics
(AAP) regarding the management of infantile hemangiomas (IHs). Similar consensus …

A randomized, controlled trial of oral propranolol in infantile hemangioma

C Léauté-Labrèze, P Hoeger… - … England Journal of …, 2015 - Mass Medical Soc
Background Oral propranolol has been used to treat complicated infantile hemangiomas,
although data from randomized, controlled trials to inform its use are limited. Methods We …

Initiation and use of propranolol for infantile hemangioma: report of a consensus conference

BA Drolet, PC Frommelt, SL Chamlin, A Haggstrom… - …, 2013 - publications.aap.org
Infantile hemangiomas (IHs) are common neoplasms composed of proliferating endothelial-
like cells. Despite the relative frequency of IH and the potential severity of complications …

Propranolol for infantile haemangiomas: insights into the molecular mechanisms of action

CH Storch, PH Hoeger - British Journal of Dermatology, 2010 - academic.oup.com
Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

Diagnosis and management of infantile hemangioma

DH Darrow, AK Greene, AJ Mancini, AJ Nopper… - …, 2015 - publications.aap.org
Infantile hemangiomas (IHs) are the most common tumors of childhood. Unlike other tumors,
they have the unique ability to involute after proliferation, often leading primary care …

Safety of oral propranolol for the treatment of infantile hemangioma: a systematic review

C Leaute-Labreze, O Boccara… - …, 2016 - publications.aap.org
METHODS: We searched Embase and Medline databases (2007–July 2014) and
unpublished data from the manufacturer of Hemangiol/Hemangeol (marketed pediatric …

A randomized controlled trial of propranolol for infantile hemangiomas

M Hogeling, S Adams, O Wargon - Pediatrics, 2011 - publications.aap.org
OBJECTIVE: Propranolol hydrochloride is a safe and effective medication for treating
infantile hemangiomas (IHs), with decreases in IH volume, color, and elevation. METHODS …

Propranolol and infantile hemangiomas four years later: a systematic review

AL Marqueling, V Oza, IJ Frieden… - Pediatric …, 2013 - Wiley Online Library
To systematically review the literature evaluating efficacy and adverse events of propranolol
treatment for infantile hemangiomas, we searched the MEDLINE and Cochrane databases …

Sirolimus for the treatment of children with various complicated vascular anomalies

H Lackner, A Karastaneva, W Schwinger… - European journal of …, 2015 - Springer
Vascular anomalies include a heterogeneous group of disorders that are categorized as
vascular tumors or vascular malformations. Treatment options include resection …