Hypoxaemia and risk of death among children: rethinking oxygen saturation, risk-stratification, and the role of pulse oximetry in primary care
Pulse oximeters are essential for assessing blood oxygen levels in emergency departments,
operating theatres, and hospital wards. However, although the role of pulse oximeters in …
operating theatres, and hospital wards. However, although the role of pulse oximeters in …
The impact of pulse oximetry on diagnosis, management and outcomes of acute febrile illness in low-income and middle-income countries: a systematic review
Background Acute fever is a common presenting symptom in low/middle-income countries
(LMICs) and is strongly associated with sepsis. Hypoxaemia predicts disease severity in …
(LMICs) and is strongly associated with sepsis. Hypoxaemia predicts disease severity in …
Prognostic accuracy of biomarkers of immune and endothelial activation in Mozambican children hospitalized with pneumonia
Pneumonia is a leading cause of child mortality. However, currently we lack simple,
objective, and accurate risk-stratification tools for pediatric pneumonia. Here we test the …
objective, and accurate risk-stratification tools for pediatric pneumonia. Here we test the …
Defining the role of host biomarkers in the diagnosis and prognosis of the severity of childhood pneumonia: a prospective cohort study
Reliable tools to inform outpatient management of childhood pneumonia in resource-limited
settings are needed. We investigated the value added by biomarkers of the host infection …
settings are needed. We investigated the value added by biomarkers of the host infection …
ePOCT+ and the medAL-suite: Development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients in low- and middle …
Electronic clinical decision support algorithms (CDSAs) have been developed to address
high childhood mortality and inappropriate antibiotic prescription by helping clinicians …
high childhood mortality and inappropriate antibiotic prescription by helping clinicians …
Analytical performance of 17 commercially available point-of-care tests for CRP to support patient management at lower levels of the health system
S Calarco, BL Fernandez-Carballo, T Keller, S Weber… - Plos one, 2023 - journals.plos.org
Accurate and precise point-of-care (POC) testing for C-reactive protein (CRP) can help
support healthcare providers in the clinical management of patients. Here, we compared the …
support healthcare providers in the clinical management of patients. Here, we compared the …
Hypoxaemia prevalence and management among children and adults presenting to primary care facilities in Uganda: a prospective cohort study
Hypoxaemia (low blood oxygen) is common among hospitalised patients, increasing the
odds of death five-fold and requiring prompt detection and treatment. However, we know …
odds of death five-fold and requiring prompt detection and treatment. However, we know …
Innovative strategies for the surveillance, prevention, and management of pediatric infections applied to low-income settings
D Torres-Fernandez, J Dalsuco, J Bramugy… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Infectious diseases still cause a significant burden of morbidity and mortality
among children in low-and middle-income countries (LMICs). There are ample opportunities …
among children in low-and middle-income countries (LMICs). There are ample opportunities …
Host biomarkers reflect prognosis in patients presenting with moderate coronavirus disease 2019: a prospective cohort study
Efficient resource allocation is essential for effective pandemic response. We measured host
biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found …
biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found …
sTREM-1 to Risk-Stratify Patients With Malaria: A Functional Crystal Ball to Improve Outcomes and Save Lives
The past 2 decades have brought substantial innovation in the prevention, diagnosis, and
management of malaria, contributing to an overall better control of this disease, a more …
management of malaria, contributing to an overall better control of this disease, a more …