Strategies to increase nitric oxide signalling in cardiovascular disease
JO Lundberg, MT Gladwin, E Weitzberg - Nature reviews Drug …, 2015 - nature.com
Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …
Human nitric oxide synthase—Its functions, polymorphisms, and inhibitors in the context of inflammation, diabetes and cardiovascular diseases
M Król, M Kepinska - International journal of molecular sciences, 2020 - mdpi.com
In various diseases, there is an increased production of the free radicals needed to carry out
certain physiological processes but their excessive amounts can cause oxidative stress and …
certain physiological processes but their excessive amounts can cause oxidative stress and …
Glycyrrhetinic acid induces oxidative/nitrative stress and drives ferroptosis through activating NADPH oxidases and iNOS, and depriving glutathione in triple-negative …
Reactive oxygen species (ROS)/reactive nitrogen species (RNS)-mediated ferroptosis
becomes a novel effective target for anti-cancer treatment. In the present study, we tested the …
becomes a novel effective target for anti-cancer treatment. In the present study, we tested the …
Nitric oxide and peroxynitrite in health and disease
P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate‐nitrite‐nitric oxide pathway
S Lidder, AJ Webb - British journal of clinical pharmacology, 2013 - Wiley Online Library
The discovery that dietary (inorganic) nitrate has important vascular effects came from the
relatively recent realization of the 'nitrate‐nitrite‐nitric oxide (NO) pathway'. Dietary nitrate …
relatively recent realization of the 'nitrate‐nitrite‐nitric oxide (NO) pathway'. Dietary nitrate …
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
Aggregated α-synuclein proteins form brain lesions that are hallmarks of neurodegenerative
synucleinopathies, and oxidative stress has been implicated in the pathogenesis of some of …
synucleinopathies, and oxidative stress has been implicated in the pathogenesis of some of …
Oxidative and nitrative stress in neurodegeneration
CA Cobb, MP Cole - Neurobiology of disease, 2015 - Elsevier
Aerobes require oxygen for metabolism and normal free radical formation. As a result,
maintaining the redox homeostasis is essential for brain cell survival due to their high …
maintaining the redox homeostasis is essential for brain cell survival due to their high …
[图书][B] Oxidation and antioxidants in organic chemistry and biology
ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …
compounds and polymers, and biological processes mediated by free radicals, Oxidation …
The effects of oxidative stress on the development of atherosclerosis
M Khosravi, A Poursaleh, G Ghasempour… - Biological …, 2019 - degruyter.com
Atherosclerosis is a cardiovascular disease (CVD) known widely world wide. Several
hypothesizes are suggested to be involved in the narrowing of arteries during process of …
hypothesizes are suggested to be involved in the narrowing of arteries during process of …
[HTML][HTML] Chemistry of phospholipid oxidation
A Reis, CM Spickett - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2012 - Elsevier
The oxidation of lipids has long been a topic of interest in biological and food sciences, and
the fundamental principles of non-enzymatic free radical attack on phospholipids are well …
the fundamental principles of non-enzymatic free radical attack on phospholipids are well …