Introduction Although many studies examine purported risks associated with sexual
activities, few examine potential physical and mental health benefits, and even fewer …

Male infertility has affected many families around the world. However, due to the mechanism
underlying male reproductive system dysfunction are not completely elucidated, the use of …

Sildenafil (Viagra®) has recently been found to have a neuroprotective effect, which occurs
through the inhibition of inflammation and demyelination in the cerebellum. However, the …

Contents The aim of the present study was to evaluate the in vitro and in vivo effect of the
addition of superoxide dismutase (SOD) and reduced glutathione (GSH) to ram semen …

High systemic exposures to calcitriol are necessary for optimal antitumor effects. Human
prostate cancer PC3 cells are insensitive to calcitriol treatment. Therefore, we investigated …

Introduction The biological importance of testosterone is generally accepted by the medical
community; however, controversy focuses on its relevance to sexual function and the sexual …

Several studies reveal that vitamin E acts as a cellular stabilizer of unsaturated lipids against
oxidative deterioration, thus maintaining structural and functional integrity at the subcellular …

Ethnopharmacological relevance Psychological stress is a growing global threat to male
sexual potency and erection efficiency. Withania somnifera (L.) Dunal (WS), also known as …

Objective Type 2 diabetes mellitus (T2DM) is associated with endothelial dysfunction,
characterized by a reduction of nitric oxide (NO)-mediated relaxation. Phosphodiesterase …

Abstract Type 5 phosphodiesterase (PDE5) blockade by inhibitors (PDE5i) results in
intracellular cyclic guanosine monophosphate (cGMP) increase and smooth muscle …