The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Lead (Pb) exposure and heart failure risk

Z Chen, X Huo, G Chen, X Luo, X Xu - Environmental Science and …, 2021 - Springer
Lead (Pb) is a heavy metal with widespread industrial use, but it is also a widespread
environmental contaminant with serious toxicological consequences to many species. Pb …

The association between homocysteine and ischemic stroke subtypes in Chinese: a meta-analysis

T Zhang, Y Jiang, S Zhang, T Tie, Y Cheng, X Su… - Medicine, 2020 - journals.lww.com
Background: The findings on the association between elevated plasma homocysteine levels
and the risk of the trial of org 10172 in acute stroke treatment (TOAST) of ischemic stroke …

Hyperhomocysteinemia in cardiovascular diseases: revisiting observational studies and clinical trials

JL Guéant, RM Guéant-Rodriguez… - Thrombosis and …, 2023 - thieme-connect.com
Thromboembolic manifestations are relatively frequent in patients with intermediate/severe
hyperhomocysteinemia (> 30 µmol/L) related to inherited disorders and deficiencies in …

Homocysteine and stroke risk: modifying effect of methylenetetrahydrofolate reductase C677T polymorphism and folic acid intervention

M Zhao, X Wang, M He, X Qin, G Tang, Y Huo, J Li… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Elevated blood homocysteine concentration increases the risk of
stroke, especially among hypertensive individuals. Homocysteine is largely affected by the …

The role of homocysteine levels as a risk factor of ischemic stroke events: A systematic review and meta-analysis

RT Pinzon, VO Wijaya, V Veronica - Frontiers in Neurology, 2023 - frontiersin.org
Introduction Among numerous risk factors, homocysteine (Hcy) has been linked to cerebral
infarction; however, results have been inconsistent. This review aimed to conduct a meta …

Highlights of the 2018 Chinese hypertension guidelines

J Liu - Clinical hypertension, 2020 - Springer
Background Blood pressure (BP) are uncontrolled in over 80% hypertensive population in
China, indicating a compelling need for a pragmatic hypertension management strategy …

[PDF][PDF] 中国脑卒中流行概况

吴亚哲, 陈伟伟 - 心脑血管病防治, 2016 - img.vpdchina.com
脑卒中具有发病率高, 致死率高和复发率高等特点, 2008 年公布的中国居民第三次死因抽样调查
显示, 脑血管病是中国国民第一位死亡原因[1]. 世界卫生组织MONICA 研究表明 …

Status of hyperhomocysteinemia in China: results from the China stroke high-risk population screening program, 2018

W Tu, F Yan, B Chao, X Ji, L Wang - Frontiers of Medicine, 2021 - Springer
A nationwide survey was conducted from October 2018 to September 2019 to assess the
prevalence of hyperhomocysteinemia (Hhcy) and its influencing factors in China. A …

H-type hypertension and risk of stroke in chinese adults: A prospective, nested case–control study

J Li, S Jiang, Y Zhang, G Tang, Y Wang… - Journal of translational …, 2015 - degruyter.com
Objectives: To investigate the independent and joint associations of hyperhomocysteinemia
and hypertension with incident stroke and stroke death in Chinese adults. Methods: About …