Severe cardiac remodeling leading to heart failure in individuals harboring pathogenic
LMNA variants, known as cardiolaminopathy, poses a significant clinical challenge …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

Delineating human cardiac pathologies and their basic molecular mechanisms relies on
research conducted in model organisms. Yet translating findings from preclinical models to …

Although the prevalence of heart failure with preserved ejection fraction (HFpEF) is
increasing, evidence-based therapies for HFpEF remain limited, likely due to an incomplete …

Cardiac fibroblasts (CFs) represent a major subpopulation of cells in the developing and
adult heart. Cardiomyocyte (CM) and CF intercellular communication occurs through …

Protein diversity can increase via N-myristoylation, adding myristic acid to an N-terminal
glycine residue. In a murine model of pressure overload, knockdown of cardiac N …

Study of the molecular basis of myocardial fibrosis is hampered by limited access to tissues
from human patients and by confounding variables associated with sample accessibility …

In this perspective, we discussed emerging data indicating a role for Notch signalling in
inherited disorders of the heart failure with focus on hypertrophic cardiomyopathy (HCM) …

Citrate-modified silver nanoparticles (AgNP-cit) have received extensive attention due to
their excellent antimicrobial properties. However, these particles tend to migrate in vivo …

Engineering a conduction‐consistent cardiac patch has direct implications to biomedical
research. However, there is difficulty in obtaining and maintaining a system that allows …