Innovations in sequencing technologies have allowed biologists to make incredible
advances in understanding biological systems. As experience grows, researchers …

Variants within non-coding genomic regions can greatly affect disease. In recent years,
increasing focus has been given to these variants, and how they can alter regulatory …

Bioinformatics applications increasingly rely on ad hoc disk storage of k-mer sets, eg for de
Bruijn graphs or alignment indexes. Here, we introduce the K-mer File Format as a general …

We used long read sequencing data generated from Knightia excelsa, a nectar‐producing
Proteaceae tree endemic to Aotearoa (New Zealand), to explore how sequencing data type …

While fastidious microbes can be abundant and ubiquitous in their natural communities,
many fail to grow axenically in laboratories due to auxotrophies or other dependencies. To …

The capability to generate densely sampled single nucleotide polymorphism (SNP) data is
essential in diverse subdisciplines of biology, including crop breeding, pathology, forensics …

Since their emergence around 2006, Next-Generation Sequencing technologies have been
revolutionizing biological and medical research. Obtaining instantly an extensive amount of …

Background Currently available short read genome assemblies of the tetraploid protozoan
parasite Giardia intestinalis are highly fragmented, highlighting the need for improved …

Aim Oceanic islands have played an important role in our understanding of the
diversification of organisms, and phylogenetic estimates have been used in this context to …

While fastidious microbes can be abundant and ubiquitous in their natural communities,
many fail to grow axenically in laboratories due to auxotrophies or other dependencies. To …