Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most
of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane …

This is a sequel to the previous Perspective “The CH–π hydrogen bond in chemistry.
Conformation, supramolecules, optical resolution and interactions involving carbohydrates” …

The plasma membrane of eukaryotic cells contains several types of lipids displaying high
biochemical variability in both their apolar moiety (eg, the acyl chain of glycerolipids) and …

Major depression and anxiety disorders have high prevalence rates and are frequently
comorbid. The neurobiological bases for these disorders are not fully understood, and …

The bulk structure of biological membranes consists of a bilayer of amphipathic lipids.
According to the fluid mosaic model proposed by Singer and Nicholson, the …

Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Simple sphingolipids such as ceramide and sphingomyelin (SM) as well as more complex
glycosphingolipids play very important roles in cell function under physiological conditions …

Many types of ion channel localize to cholesterol and sphingolipid‐enriched regions of the
plasma membrane known as lipid microdomains or 'rafts'. The precise physiological role of …

A better understanding of the cellular physiological role that plasma membrane lipids, fatty
acids and sterols play in various cellular systems may yield more insight into how cellular …