Quantitative Online Monitoring of an Immobilized Enzymatic Network by Ion Mobility–Mass Spectrometry

Q Duez, J van de Wiel, B van Sluijs… - Journal of the …, 2024 - ACS Publications
The forward design of in vitro enzymatic reaction networks (ERNs) requires a detailed
analysis of network kinetics and potentially hidden interactions between the substrates and …

Competing Mechanisms in Palladium-Catalyzed Alkoxycarbonylation of Styrene

J Mehara, M Anania, P Kocovsky, J Roithová - ACS catalysis, 2024 - ACS Publications
Palladium-catalyzed carbonylation is a versatile method for the synthesis of various
aldehydes, esters, lactones, or lactams. Alkoxycarbonylation of alkenes with carbon …

Autocatalysis in Eschenmoser Coupling Reactions

Q Duez, L Marek, J Váňa, J Hanusek… - … –A European Journal, 2024 - Wiley Online Library
The Eschenmoser coupling reaction (ECR) of thioamides with electrophiles is believed to
proceed via thiirane intermediates. However, little is known about converting the …

Analytical Chemistry Seminar

J Roithova - apps.science.purdue.edu
Mass spectrometry is an established tool in reaction monitoring and studying reaction
intermediates.[1] The nonlinear ionization response and, thus, the inability to obtain …