Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …

Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …

The reduced therapeutic efficacy of rizatriptan in migraine treatment is primarily due to low
oral bioavailability and extensive first pass metabolism. The purpose of this investigation …

Abstract Three-dimensional (3D) printing has recently appeared as one of the most
promising additive manufacturing techniques to fabricate 3D objects, with uses spanning …

Highlights•The buccal route has been exploited for selected potent small
molecules.•Research to achieve buccal insulin delivery is based on avoiding the …

The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based
tactic to address population-specific issues. However, the off-label prescription of adult …

The development of pediatric-specific dose forms is particularly difficult due to a variety of
factors relating to pediatric population differences from adult populations. The buccal …

A great number of patients have difficulty swallowing or needle fear. Therefore, buccal and
orodispersible dosage forms (ODFs) represent an important strategy to enhance patient …

The aqueous solution of binary mixtures of amphiphilic copolymers is a potential platform for
fabricating mixed polymeric micelles for pharmaceutical applications, particularly in …

Fast dissolving oral preparations have unique advantages such as rapid dissolution, fast
onset of action, convenient administration, and enhanced bioavailability. Therefore, these …