Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …

Objective We explore here a novel model for amyloidogenesis in Alzheimer's disease (AD).
This new perspective on AD amyloidosis seeks to provide a rational framework for …

Antimicrobial peptides (AMPs) are known to have family-specific sequence composition,
which can be mined for discovery and design of AMPs. Here, we present CAMPR3; an …

There is increasing evidence that food is an important factor that influences and shapes the
composition and configuration of the gut microbiota. Most studies have focused on …

Chronic obstructive pulmonary disease (COPD), a major cause of death and morbidity
worldwide, is characterized by expiratory airflow limitation that is not fully reversible …

The gut microbiome is extremely important for maintaining homeostasis with host intestinal
epithelial, neuronal, and immune cells and this host-microbe interaction is critical during …

Amyloid plaques, the hallmark of Alzheimer's disease (AD), contain fibrillar β-amyloid (Aβ) 1-
40 and 1-42 peptides. Herpes simplex virus 1 (HSV-1) has been implicated as a risk factor …

The plasma membrane, which encapsulates human cells, is composed of a complex mixture
of lipids and embedded proteins. Emerging knowledge points towards the lipids as having a …

Vitamin A (VA) is critical for many biological processes, including embryonic development,
hormone production and function, the maintenance and modulation of immunity, and the …