Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Inflammatory disorders of the skeletal muscle include polymyositis (PM), dermatomyositis
(DM),(immune mediated) necrotizing myopathy (NM), overlap syndrome with myositis …

Alzheimer's disease is a common and devastating disease characterized by aggregation of
the amyloid-β peptide. However, we know relatively little about the underlying molecular …

Inclusion body myositis (IBM) is often viewed as an enigmatic disease with uncertain
pathogenic mechanisms and confusion around diagnosis, classification and prospects for …

Objective We previously identified a circulating autoantibody against a 43 kDa muscle
autoantigen in sporadic inclusion body myositis (IBM) and demonstrated the feasibility of an …

Objectives Myositis is a heterogeneous family of diseases that includes dermatomyositis
(DM), antisynthetase syndrome (AS), immune-mediated necrotising myopathy (IMNM) …

Autoimmune diseases develop as a result of chronic inflammation owing to interactions
between genes and the environment. However, the mechanisms by which autoimmune …

Objective Sporadic inclusion body myositis (sIBM) is an inflammatory myopathy
characterized by both degenerative and autoimmune features. In contrast to other …

Idiopathic inflammatory myopathies (IIM) are a group of chronic, autoimmune conditions
affecting primarily the proximal muscles. The most common types are dermatomyositis (DM) …

Inclusion body myositis is the most common acquired muscle disease in older individuals,
and its prevalence varies among countries and ethnic groups. The aetiology and …