Tailored biosensors for drug screening, efficacy assessment, and toxicity evaluation

Y Tao, L Chen, M Pan, F Zhu, D Zhu - ACS sensors, 2021 - ACS Publications
Biosensors have been flourishing in the field of drug discovery with pronounced
developments in the past few years. They facilitate the screening and discovery of innovative …

Novel and efficient techniques in the discovery of antioxidant peptides

Y Zhang, Y Li, T Ren, P Xiao, J Duan - Critical Reviews in Food …, 2023 - Taylor & Francis
As a research hotspot in food science and nutrition, antioxidant peptides can function by
scavenging free radicals, inhibiting peroxides, and chelating metal ions. Therefore, how to …

Reagentless biomolecular analysis using a molecular pendulum

J Das, S Gomis, JB Chen, H Yousefi, S Ahmed… - Nature …, 2021 - nature.com
The development of reagentless sensors that can detect molecular analytes in biological
fluids could enable a broad range of applications in personalized health monitoring …

Capillary-assisted molecular pendulum bioanalysis

H Zargartalebi, H Yousefi, CD Flynn… - Journal of the …, 2022 - ACS Publications
The development of robust biosensing strategies that can be easily implemented in
everyday life remains a challenge for the future of modern biosensor research. While several …

[HTML][HTML] RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not

MW Webster, JAW Stowell, LA Passmore - Elife, 2019 - elifesciences.org
The Ccr4-Not complex removes mRNA poly (A) tails to regulate eukaryotic mRNA stability
and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4 …

Kinetic microscale thermophoresis for simultaneous measurement of binding affinity and kinetics

JAC Stein, A Ianeselli, D Braun - Angewandte Chemie, 2021 - Wiley Online Library
Microscale thermophoresis (MST) is a versatile technique to measure binding affinities of
binder–ligand systems, based on the directional movement of molecules in a temperature …

[HTML][HTML] Protein analysis by time-resolved measurements with an electro-switchable DNA chip

A Langer, PA Hampel, W Kaiser, J Knezevic… - Nature …, 2013 - nature.com
Measurements in stationary or mobile phases are fundamental principles in protein analysis.
Although the immobilization of molecules on solid supports allows for the parallel analysis of …

[HTML][HTML] Label-free methods for optical in vitro characterization of protein–protein interactions

F Soltermann, WB Struwe, P Kukura - Physical Chemistry Chemical …, 2021 - pubs.rsc.org
Protein–protein interactions are involved in the regulation and function of the majority of
cellular processes. As a result, much effort has been aimed at the development of …

[HTML][HTML] Biosensors based on the binding events of nitrilotriacetic acid–metal complexes

L Zhu, Y Chang, Y Li, M Qiao, L Liu - Biosensors, 2023 - mdpi.com
Molecular immobilization and recognition are two key events for the development of
biosensors. The general ways for the immobilization and recognition of biomolecules …

Extraction, detection, and profiling of serum biomarkers using designed Fe3O4@SiO2@HA core–shell particles

C Rejeeth, X Pang, R Zhang, W Xu, X Sun, B Liu, J Lou… - Nano Research, 2018 - Springer
Serum biomarkers in the form of proteins (eg cluster of differentiation-44 (CD44)) have been
demonstrated to have high clinical sensitivity and specificity for disease diagnosis and …