Multiscale PHATE identifies multimodal signatures of COVID-19
As the biomedical community produces datasets that are increasingly complex and high
dimensional, there is a need for more sophisticated computational tools to extract biological …
dimensional, there is a need for more sophisticated computational tools to extract biological …
Single-cell analysis reveals inflammatory interactions driving macular degeneration
Due to commonalities in pathophysiology, age-related macular degeneration (AMD)
represents a uniquely accessible model to investigate therapies for neurodegenerative …
represents a uniquely accessible model to investigate therapies for neurodegenerative …
Mapping phenotypic plasticity upon the cancer cell state landscape using manifold learning
Phenotypic plasticity describes the ability of cancer cells to undergo dynamic, nongenetic
cell state changes that amplify cancer heterogeneity to promote metastasis and therapy …
cell state changes that amplify cancer heterogeneity to promote metastasis and therapy …
Building and analyzing metacells in single-cell genomics data
M Bilous, L Hérault, AAG Gabriel… - Molecular Systems …, 2024 - embopress.org
The advent of high-throughput single-cell genomics technologies has fundamentally
transformed biological sciences. Currently, millions of cells from complex biological tissues …
transformed biological sciences. Currently, millions of cells from complex biological tissues …
Structural and developmental principles of neuropil assembly in C. elegans
Neuropil is a fundamental form of tissue organization within the brain, in which densely
packed neurons synaptically interconnect into precise circuit architecture,. However, the …
packed neurons synaptically interconnect into precise circuit architecture,. However, the …
Taxonomy of benchmarks in graph representation learning
Abstract Graph Neural Networks (GNNs) extend the success of neural networks to graph-
structured data by accounting for their intrinsic geometry. While extensive research has been …
structured data by accounting for their intrinsic geometry. While extensive research has been …
Multiscale geometric and topological analyses for characterizing and predicting immune responses from single cell data
Single cell genomics has revolutionized our ability to map immune heterogeneity and
responses. With the influx of large-scale data sets from diverse modalities, the resolution …
responses. With the influx of large-scale data sets from diverse modalities, the resolution …
[PDF][PDF] Cuts: A deep learning and topological framework for multigranular unsupervised medical image segmentation
Segmenting medical images is critical to facilitating both patient diagnoses and quantitative
research. A major limiting factor is the lack of labeled data, as obtaining expert annotations …
research. A major limiting factor is the lack of labeled data, as obtaining expert annotations …
Multiscale PHATE exploration of SARS-CoV-2 data reveals multimodal signatures of disease
The biomedical community is producing increasingly high dimensional datasets, integrated
from hundreds of patient samples, which current computational techniques struggle to …
from hundreds of patient samples, which current computational techniques struggle to …
[PDF][PDF] Cuts: A framework for multigranular unsupervised medical image segmentation
Segmenting medical images is critical to facilitating both patient diagnoses and quantitative
research. A major limiting factor is the lack of labeled data, as obtaining expert annotations …
research. A major limiting factor is the lack of labeled data, as obtaining expert annotations …