[HTML][HTML] Protective role of melatonin and its metabolites in skin aging
G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …
Melatonin as an antioxidant: under promises but over delivers
Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …
number of circumstances. It achieves this action via a variety of means: direct detoxification …
Melatonin as a natural ally against oxidative stress: a physicochemical examination
Oxidative stress has been proven to be related to the onset of a large number of health
disorders. This chemical stress is triggered by an excess of free radicals, which are …
disorders. This chemical stress is triggered by an excess of free radicals, which are …
Melatonin membrane receptors in peripheral tissues: distribution and functions
RM Slominski, RJ Reiter… - Molecular and cellular …, 2012 - Elsevier
Many of melatonin's actions are mediated through interaction with the G-protein coupled
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or …
membrane bound melatonin receptors type 1 and type 2 (MT1 and MT2, respectively) or …
One molecule, many derivatives: a never‐ending interaction of melatonin with reactive oxygen and nitrogen species?
DX Tan, LC Manchester, MP Terron… - Journal of pineal …, 2007 - Wiley Online Library
Melatonin is a highly conserved molecule. Its presence can be traced back to ancient
photosynthetic prokaryotes. A primitive and primary function of melatonin is that it acts as a …
photosynthetic prokaryotes. A primitive and primary function of melatonin is that it acts as a …
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger
Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …
[HTML][HTML] Interplay between ROS and antioxidants during ischemia-reperfusion injuries in cardiac and skeletal muscle
Ischemia reperfusion (IR), present in myocardial infarction or extremity injuries, is a major
clinical issue and leads to substantial tissue damage. Molecular mechanisms underlying IR …
clinical issue and leads to substantial tissue damage. Molecular mechanisms underlying IR …
Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin
The discovery of melatonin and its derivatives as antioxidants has stimulated a very large
number of studies which have, virtually uniformly, documented the ability of these molecules …
number of studies which have, virtually uniformly, documented the ability of these molecules …
Significance of melatonin in antioxidative defense system: reactions and products
Melatonin is a potent endogenous free radical scavenger, actions that are independent of its
many receptor-mediated effects. In the last several years, hundreds of publications have …
many receptor-mediated effects. In the last several years, hundreds of publications have …
The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives
Melatonin is an uncommonly widely distributed molecule. It is found throughout the plant
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …