Rheumatoid arthritis: extra-articular manifestations and comorbidities

FA Figus, M Piga, I Azzolin, R McConnell… - Autoimmunity reviews, 2021 - Elsevier
Although synovitis is the pathological hallmark of rheumatoid arthritis (RA), many extra-
articular manifestations (EMs) and comorbidities likely occur due to the complex, chronic …

Treatment of coronary microvascular dysfunction

CN Bairey Merz, CJ Pepine… - Cardiovascular …, 2020 - academic.oup.com
Contemporary data indicate that patients with signs and symptoms of ischaemia and non-
obstructive coronary artery disease (INOCA) often have coronary microvascular dysfunction …

Complexity of TNF-α signaling in heart disease

F Rolski, P Błyszczuk - Journal of clinical medicine, 2020 - mdpi.com
Heart disease is a leading cause of death with unmet clinical needs for targeted treatment
options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine …

Cardiovascular effects of approved drugs for rheumatoid arthritis

F Atzeni, J Rodríguez-Carrio, CD Popa… - Nature Reviews …, 2021 - nature.com
The risk of cardiovascular disease is increased in patients with rheumatoid arthritis
compared with the general population owing to the influence of traditional and non …

Cardiovascular co-morbidity in patients with rheumatoid arthritis: a narrative review of risk factors, cardiovascular risk assessment and treatment

A Jagpal, I Navarro-Millán - BMC rheumatology, 2018 - Springer
Cardiovascular disease (CVD) is markedly increased in patients with rheumatoid arthritis
partly due to accelerated atherosclerosis from chronic inflammation. Traditional …

Comprehensive Management of ANOCA, Part 2—Program Development, Treatment, and Research Initiatives: JACC State-of-the-Art Review

NR Smilowitz, M Prasad, RJ Widmer, O Toleva… - Journal of the American …, 2023 - jacc.org
Centers specializing in coronary function testing are critical to ensure a systematic approach
to the diagnosis and treatment of angina with nonobstructive coronary arteries (ANOCA) …

Role of the eNOS uncoupling and the nitric oxide metabolic pathway in the pathogenesis of autoimmune rheumatic diseases

A Łuczak, M Madej, A Kasprzyk… - Oxidative Medicine and …, 2020 - Wiley Online Library
Atherosclerosis and its clinical complications constitute the major healthcare problems of the
world population. Due to the central role of endothelium throughout the atherosclerotic …

Anti‐Inflammatory Effects of p‐Coumaric Acid, a Natural Compound of Oldenlandia diffusa, on Arthritis Model Rats

H Zhu, Q Liang, X Xiong, Y Wang… - Evidence‐Based …, 2018 - Wiley Online Library
Objectives. In China, Oldenlandia diffusa (OD) is a natural herb that is widely used and has
been proven to be effective in the treatment of rheumatoid arthritis (RA). This study aimed to …

Accelerated atherosclerosis in rheumatoid arthritis: a systematic review

R Raj, S Thomas, V Gorantla - F1000Research, 2023 - pmc.ncbi.nlm.nih.gov
Background: Rheumatoid arthritis (RA) is a highly prevalent, chronic inflammatory condition
of the synovial joints that affects approximately 1% of the global population. The …

Novel nano therapeutic materials for the effective treatment of rheumatoid arthritis-recent insights

K Janakiraman, V Krishnaswami, V Rajendran… - Materials Today …, 2018 - Elsevier
Rheumatoid arthritis (RA) is the most common complex multifactorial joint related
autoimmune inflammatory disease with unknown etiology accomplished with increased …