Natural killer cells in antiviral immunity

NK Björkström, B Strunz, HG Ljunggren - Nature Reviews Immunology, 2022 - nature.com
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19

T Matsuyama, SK Yoshinaga, K Shibue… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 vaccinations have greatly reduced COVID-19 cases, but we must continue to
develop our understanding of the nature of the disease and its effects on human immunity …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

[HTML][HTML] Role of myeloid-derived suppressor cells in viral respiratory infections; Hints for discovering therapeutic targets for COVID-19

K Koushki, M Salemi, SM Miri, Y Arjeini… - Biomedicine & …, 2021 - Elsevier
The expansion of myeloid-derived suppressor cells (MDSCs), known as heterogeneous
population of immature myeloid cells, is enhanced during several pathological conditions …

Inhibitory immune checkpoint receptors and ligands as prognostic biomarkers in COVID-19 patients

MA Al-Mterin, A Alsalman, E Elkord - Frontiers in immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2. During T-cell activation,
the immune system uses different checkpoint pathways to maintain co-inhibitory and co …

Immune-guided therapy of COVID-19

G Ferraccioli, E Gremese, D Goletti, L Petrone… - Cancer Immunology …, 2022 - AACR
Vaccination has been a game changer in our efforts to address the coronavirus disease
2019 (COVID-19) pandemic. However, the disease might still represent a clinical crisis for …

Myeloid-derived suppressor cells in COVID-19: A review

YV Perfilyeva, YO Ostapchuk, R Tleulieva, A Kali… - Clinical …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a potentially life-threatening infection
characterized by excessive inflammation, coagulation disorders and organ damage. A …

A metagenomic DNA sequencing assay that is robust against environmental DNA contamination

O Mzava, AP Cheng, A Chang, S Smalling… - Nature …, 2022 - nature.com
Metagenomic DNA sequencing is a powerful tool to characterize microbial communities but
is sensitive to environmental DNA contamination, in particular when applied to samples with …

[HTML][HTML] SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells

Q Hammer, J Dunst, W Christ, F Picarazzi, M Wendorff… - Cell reports, 2022 - cell.com
Natural killer (NK) cells are innate immune cells that contribute to host defense against virus
infections. NK cells respond to severe acute respiratory syndrome coronavirus 2 (SARS-CoV …