Chemical mapping of tumor progression by FT-IR imaging: towards molecular histopathology

C Petibois, G Déléris - TRENDS in Biotechnology, 2006 - cell.com
Fourier-transform infrared (FT-IR) spectro-imaging enables global analysis of samples, with
resolution close to the cellular level. Recent studies have shown that FT-IR imaging enables …

Applications of mid-infrared spectroscopy in the clinical laboratory setting

S De Bruyne, MM Speeckaert… - Critical reviews in clinical …, 2018 - Taylor & Francis
Fourier transform mid-infrared (MIR-FTIR) spectroscopy is a nondestructive, label-free,
highly sensitive and specific technique that provides complete information on the chemical …

Fourier-transform infrared spectroscopy coupled with a classification machine for the analysis of blood plasma or serum: a novel diagnostic approach for ovarian …

K Gajjar, J Trevisan, G Owens, PJ Keating, NJ Wood… - Analyst, 2013 - pubs.rsc.org
Currently available screening tests do not deliver the required sensitivity and specificity for
accurate diagnosis of ovarian or endometrial cancer. Infrared (IR) spectroscopy of blood …

The detection and discrimination of human body fluids using ATR FT-IR spectroscopy

CM Orphanou - Forensic science international, 2015 - Elsevier
Blood, saliva, semen and vaginal secretions are the main human body fluids encountered at
crime scenes. Currently presumptive tests are routinely utilised to indicate the presence of …

[HTML][HTML] Spectroscopy goes viral: Diagnosis of hepatitis B and C virus infection from human sera using ATR-FTIR spectroscopy

S Roy, D Perez-Guaita, S Bowden, P Heraud… - Clinical …, 2019 - Elsevier
The development of a new fast, portable and reagent-free diagnostic technique for hepatitis
B (HBV) and hepatitis C (HCV) viruses would be an enormous benefit to society. Here, we …

Impact of silk biomaterial structure on proteolysis

J Brown, CL Lu, J Coburn, DL Kaplan - Acta biomaterialia, 2015 - Elsevier
The goal of this study was to determine the impact of silk biomaterial structure (eg solution,
hydrogel, film) on proteolytic susceptibility. In vitro enzymatic degradation of silk fibroin …

An empirical investigation of deviations from the Beer–Lambert law in optical estimation of lactate

M Mamouei, K Budidha, N Baishya, M Qassem… - Scientific Reports, 2021 - nature.com
The linear relationship between optical absorbance and the concentration of analytes—as
postulated by the Beer-Lambert law—is one of the fundamental assumptions that much of …

Analysis of type I and IV collagens by FT-IR spectroscopy and imaging for a molecular investigation of skeletal muscle connective tissue

C Petibois, G Gouspillou, K Wehbe, JP Delage… - Analytical and …, 2006 - Springer
Many muscular diseases result from abnormal organization of connective tissue and/or
collagen network formation. Only a few molecular imaging techniques are able to analyze …

Evaluation of nonenzymatic posttranslational modification–derived products as biomarkers of molecular aging of proteins

S Jaisson, P Gillery - Clinical chemistry, 2010 - academic.oup.com
BACKGROUND During their biological life, proteins are exposed in a cumulative fashion to
irreversible nonenzymatic, late posttranslational modifications that are responsible for their …

Vibrational biospectroscopy coupled with multivariate analysis extracts potentially diagnostic features in blood plasma/serum of ovarian cancer patients

GL Owens, K Gajjar, J Trevisan… - Journal of …, 2014 - Wiley Online Library
Despite numerous advances in “omics” research, early detection of ovarian cancer still
remains a challenge. The aim of this study was to determine whether attenuated total …