Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain
development that results in a head circumference more than 3 standard deviations below …

Centrioles are microtubule-based core components of centrosomes and cilia. They are
duplicated exactly once during S-phase progression. Central to formation of each new …

A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …

Autosomal recessive (AR) gene defects are the leading genetic cause of intellectual
disability (ID) in countries with frequent parental consanguinity, which account for about …

Autosomal recessive primary microcephaly (MCPH;“small head syndrome”) is a rare,
heterogeneous disease arising from the decreased production of neurons during brain …

Microcephaly or reduced head circumference results from a multitude of abnormal
developmental processes affecting brain growth and/or leading to brain atrophy. Autosomal …

Autosomal recessive primary microcephaly (MCPH; MicroCephaly Primary Hereditary) is a
genetically heterogeneous neurodevelopmental disorder characterized by a significantly …

Objective Rare genetic disorders resulting in prenatal or neonatal death are genetically
heterogeneous, but testing is often limited by the availability of fetal DNA, leaving couples …

Primary microcephaly (MCPH) is an autosomal recessive sporadic neurodevelopmental
ailment with a trivial head size characteristic that is below 3–4 standard deviations. MCPH is …

Primary microcephaly is a congenital neurodevelopmental disorder of reduced head
circumference and brain volume, with fewer neurons in the cortex of the developing brain …