Promising hepatoprotective effects of lycopene in different liver diseases

IM Ibrahim, HS Althagafy, EK Abd-Alhameed… - Life Sciences, 2022 - Elsevier
The incidence of liver diseases such as hepatitis, fibrosis, cirrhosis, and liver cancer is one
of the world's most significant health challenges. Liver diseases can be caused by a variety …

Lycopene mitigates DEHP-induced hepatic mitochondrial quality control disorder via regulating SIRT1/PINK1/mitophagy axis and mitochondrial unfolded protein …

Y Zhao, HX Li, Y Luo, JG Cui, M Talukder, JL Li - Environmental Pollution, 2022 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a hazardous chemical which is used as a
plasticizer in the plastic products. Lycopene (LYC) is a carotenoid that has protective roles …

Lycopene prevents DEHP-induced liver lipid metabolism disorder by inhibiting the HIF-1α-induced PPARα/PPARγ/FXR/LXR system

Y Zhao, DX Ma, HG Wang, MZ Li… - Journal of Agricultural …, 2020 - ACS Publications
Di (2-ethylhexyl) phthalate (DEHP) is a widespread pollutant that badly affects animals and
human health. Lycopene (LYC) has been used as a dietary supplement that has effective …

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen‐Induced Hepatonephrotoxicity in Wistar …

DN Eldin, HI Fahim, HY Ahmed… - Oxidative Medicine …, 2022 - Wiley Online Library
Acetaminophen, also known as N‐acetyl‐para‐aminophenol (NAPAP), is a traditional
antipyretic and analgesic that is used extensively around the world to treat colds and fevers …

Triclosan-induced liver injury in zebrafish (Danio rerio) via regulating MAPK/p53 signaling pathway

M Liu, W Ai, L Sun, F Fang, X Wang, S Chen… - … and Physiology Part C …, 2019 - Elsevier
Long-term exposure of triclosan (TCS), an important antimicrobial agent, can lead to
deleterious effects on liver growth and development. However, the related mechanisms on …

[HTML][HTML] Chia seeds oil ameliorate chronic immobilization stress-induced neurodisturbance in rat brains via activation of the antioxidant/anti-inflammatory/antiapoptotic …

NE Khalifa, AE Noreldin, AF Khafaga, M El-Beskawy… - Scientific reports, 2023 - nature.com
Chronic immobilization stress plays a key role in several neuropsychiatric disorders. This
investigation assessed the possible ameliorative effect of chia seed oil (CSO) against the …

Lycopene: A Potent Antioxidant with Multiple Health Benefits

MO Shafe, NM Gumede, TT Nyakudya… - Journal of Nutrition …, 2024 - Wiley Online Library
Lycopene is a naturally occurring carotenoid predominantly found in tomatoes and tomato‐
based products. Like other phytochemicals, it exhibits health beneficial biological activities …

Evaluation of mitochondrial dysfunction due to oxidative stress in therapeutic, toxic and lethal concentrations of tramadol

L Mohammadnejad, K Soltaninejad… - Toxicology …, 2021 - academic.oup.com
Tramadol (TR) is a centrally acting analgesic drug that is used to relieve pain. The
therapeutic (0.1–0.8 mg/l), toxic (1–2 mg/l) and lethal (> 2 mg/l) ranges were reported for TR …

Proanthocyanidin alleviates doxorubicin‐induced cardiac injury by inhibiting NF‐kB pathway and modulating oxidative stress, cell cycle, and fibrogenesis

KM Sadek, SFE Mahmoud, MF Zeweil… - … of Biochemical and …, 2021 - Wiley Online Library
This study investigated the potential mechanism (s) and the signaling pathway (s)
underlying the prophylactic effect of proanthocyanidin extract (PE) against doxorubicin …

Graviola attenuates DMBA-induced breast cancer possibly through augmenting apoptosis and antioxidant pathway and downregulating estrogen receptors

MM Zeweil, KM Sadek, NM Taha, Y El-Sayed… - … Science and Pollution …, 2019 - Springer
Breast cancer is a global public health problem where it is the second most prevalent
cancer. Historical cancer treatment with graviola has been reported. This study aimed to …