Autophagy is a process that targets various intracellular elements for degradation.
Autophagy can be non-selective—associated with the indiscriminate engulfment of cytosolic …

The covalent attachment of ubiquitin is a common regulatory mechanism in various proteins.
Although it has long been thought that the substrates of ubiquitination are limited to proteins …

Autophagy of glycogen (glycophagy) is crucial for the maintenance of cellular glucose
homeostasis and physiology in mammals. STBD1 can serve as an autophagy receptor to …

Studies have found that intermittent fasting (IF) can prevent diabetes, cancer, heart disease,
and neuropathy, while in humans it has helped to alleviate metabolic syndrome, asthma …

Autophagy, a cellular degradative process, has emerged as a key regulator of cellular
energy production and stress mitigation. Dysregulated autophagy is a common …

Aim We compared the efficacy of n3-polyunsaturated fatty acids (n3-PUFAs) and metformin
in halting the progression of non-alcoholic fatty liver disease (NAFLD) developed in the …

Pompe disease is a lysosomal storage disorder that preferentially affects muscles, and it is
caused by GAA mutation coding acid alpha‐glucosidase in lysosome and glycophagy …

Autophagy plays a vital role in sustaining cellular homeostasis and its alterations have been
implicated in the etiology of many diseases. Drugs development targeting autophagy began …

Glycogen storage diseases (GSDs) comprise a group of inherited metabolic disorders
characterized by defects in glycogen metabolism, leading to abnormal glycogen …

Cancer is recognized as the major cause of death worldwide and the most challenging
public health issues. Tumor cells exhibit molecular adaptations and metabolic reprograming …