Chemically-powered swimming and diffusion in the microscopic world

Y Zhang, H Hess - Nature Reviews Chemistry, 2021 - nature.com
The past decade has seen intriguing reports and heated debates concerning the chemically-
driven enhanced motion of objects ranging from small molecules to millimetre-size synthetic …

[HTML][HTML] Fundamentals and applications of enzyme powered micro/nano-motors

H Yuan, X Liu, L Wang, X Ma - Bioactive Materials, 2021 - Elsevier
Micro/nanomotors (MNMs) are miniaturized machines that can convert many kinds of energy
into mechanical motion. Over the past decades, a variety of driving mechanisms have been …

Enzyme purification improves the enzyme loading, self-propulsion, and endurance performance of micromotors

M Valles, S Pujals, L Albertazzi, S Sánchez - ACS nano, 2022 - ACS Publications
Enzyme-powered micro-and nanomotors make use of biocatalysis to self-propel in aqueous
media and hold immense promise for active and targeted drug delivery. Most (if not all) of …

Enzymes as active matter

S Ghosh, A Somasundar, A Sen - Annual Review of Condensed …, 2021 - annualreviews.org
Nature has designed multifaceted cellular structures to support life. Cells contain a vast
array of enzymes that collectively perform essential tasks by harnessing energy from …

Master curve of boosted diffusion for 10 catalytic enzymes

AY Jee, T Tlusty, S Granick - Proceedings of the National …, 2020 - National Acad Sciences
Molecular agitation more rapid than thermal Brownian motion is reported for cellular
environments, motor proteins, synthetic molecular motors, enzymes, and common chemical …

Enhanced diffusion and chemotaxis of enzymes

M Feng, MK Gilson - Annual Review of Biophysics, 2020 - annualreviews.org
Many enzymes appear to diffuse faster in the presence of substrate and to drift either up or
down a concentration gradient of their substrate. Observations of these phenomena, termed …

Perspective: a stirring role for metabolism in cells

J Losa, S Leupold, D Alonso‐Martinez… - Molecular Systems …, 2022 - embopress.org
Based on recent findings indicating that metabolism might be governed by a limit on the rate
at which cells can dissipate Gibbs energy, in this Perspective, we propose a new …

Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments

Z Chen, A Shaw, H Wilson… - Proceedings of the …, 2020 - National Acad Sciences
Theoretical and experimental observations that catalysis enhances the diffusion of enzymes
have generated exciting implications about nanoscale energy flow, molecular chemotaxis …

Molecular diffusivity of click reaction components: the diffusion enhancement question

N Rezaei-Ghaleh, J Agudo-Canalejo… - Journal of the …, 2022 - ACS Publications
Micrometer-sized objects are widely known to exhibit chemically driven motility in systems
away from equilibrium. Experimental observation of reaction-induced motility or …

Enzymatic micro/nanomotors in biomedicine: from single motors to swarms

S Chen, C Prado-Morales… - Journal of Materials …, 2024 - pubs.rsc.org
Micro/nanomotors (MNMs) have evolved from single self-propelled entities to versatile
systems capable of performing one or multiple biomedical tasks. When single MNMs self …