Olfactory ensheathing cells for spinal cord injury: sniffing out the issues

R Yao, M Murtaza, JT Velasquez… - Cell …, 2018 - journals.sagepub.com
Olfactory ensheathing cells (OECs) are glia reported to sustain the continuous axon
extension and successful topographic targeting of the olfactory receptor neurons …

The role of glial cells in Zika virus‐induced neurodegeneration

A Quincozes‐Santos, LD Bobermin, NLF Costa… - Glia, 2023 - Wiley Online Library
Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated
with microcephaly in neonates. However, clinical and experimental evidence indicate that …

Generation of three-dimensional multiple spheroid model of olfactory ensheathing cells using floating liquid marbles

RK Vadivelu, CH Ooi, RQ Yao, J Tello Velasquez… - Scientific reports, 2015 - nature.com
We describe a novel protocol for three-dimensional culturing of olfactory ensheathing cells
(OECs), which can be used to understand how OECs interact with other cells in three …

The glia response after peripheral nerve injury: a comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies

MJ Barton, J St John, M Clarke, A Wright… - International journal of …, 2017 - mdpi.com
The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than
the central nervous system (CNS). One reason for this difference is the difference in glial cell …

Phagocytosis by peripheral glia: Importance for nervous system functions and implications in injury and disease

L Nazareth, J St John, M Murtaza… - Frontiers in Cell and …, 2021 - frontiersin.org
The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …

Survival and integration of transplanted olfactory ensheathing cells are crucial for spinal cord injury repair: insights from the last 10 years of animal model studies

R Reshamwala, M Shah, J St John… - Cell …, 2019 - journals.sagepub.com
Olfactory ensheathing cells (OECs), the glial cells of the primary olfactory nervous system,
support the natural regeneration of the olfactory nerve that occurs throughout life. OECs thus …

Antioxidant and anti-senescence effect of metformin on mouse olfactory ensheathing cells (mOECs) may be associated with increased brain-derived neurotrophic …

A Śmieszek, Z Stręk, K Kornicka, J Grzesiak… - International journal of …, 2017 - mdpi.com
Metformin, the popular anti-diabetic drug was shown to exert multiple biological effects. The
most recent metformin gained attention as an agent that mobilizes endogenous progenitor …

Biological roles of olfactory ensheathing cells in facilitating neural regeneration: a systematic review

H Yang, BR He, DJ Hao - Molecular neurobiology, 2015 - Springer
Continuous renewal of neurons throughout life in the olfactory system is often thought to be
partially attributable to specialized glial cells called olfactory ensheathing cells (OECs) …

Engineering three-dimensional microenvironments towards in vitro disease models of the central nervous system

L Yildirimer, Q Zhang, S Kuang, CWJ Cheung… - …, 2019 - iopscience.iop.org
The central nervous system (CNS) has a highly complex biophysical and biochemical
environment. Despite decades of intensive research, it is still an enormous challenge to …

Biodegradable polymeric nanostructures in therapeutic applications: opportunities and challenges

SK Shukla, SK Shukla, PP Govender, NG Giri - RSC advances, 2016 - pubs.rsc.org
Biodegradable polymeric nanostructures (BPNs) have shown great promise in different
therapeutic applications such as diagnosis, imaging, drug delivery, cosmetics, organ …