FMRP-driven neuropathology in autistic spectrum disorder and alzheimer's disease: a losing game
L Bleuzé, V Triaca, A Borreca - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Fragile X mental retardation protein (FMRP) is an RNA binding protein (RBP) whose
absence is essentially associated to Fragile X Syndrome (FXS). As an RNA Binding Protein …
absence is essentially associated to Fragile X Syndrome (FXS). As an RNA Binding Protein …
An “omic” overview of fragile X syndrome
O Dionne, F Corbin - Biology, 2021 - mdpi.com
Simple Summary Fragile X syndrome (FXS) is a neurodevelopmental disorder and remains
the most frequent inherited cause of intellectual disability. Fragile X patients are at great risk …
the most frequent inherited cause of intellectual disability. Fragile X patients are at great risk …
Changes in neuroimmune and neuronal death markers after adolescent alcohol exposure in rats are reversed by donepezil
HS Swartzwelder, KL Healey, W Liu, K Dubester… - Scientific reports, 2019 - nature.com
Adolescent intermittent ethanol (AIE) exposure diminishes neurogenesis and dendritic spine
density in the dentate gyrus. The cholinesterase inhibitor, donepezil (Aricept), reverses AIE …
density in the dentate gyrus. The cholinesterase inhibitor, donepezil (Aricept), reverses AIE …
Dysregulation of the mTOR-FMRP pathway and synaptic plasticity in an environmental model of ASD
Abstract Autism Spectrum Disorder (ASD) is caused by genetic, epigenetic, and
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …
[HTML][HTML] The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture …
L Matelski, KPK Stietz, S Sethi, SL Taylor… - Current research in …, 2020 - Elsevier
Polychlorinated biphenyls (PCBs) are pervasive environmental contaminants implicated as
risk factors for neurodevelopmental disorders (NDDs). Immune dysregulation is another …
risk factors for neurodevelopmental disorders (NDDs). Immune dysregulation is another …
FXTAS presents with upregulation of the cytokines IL12 and TNFα
BD Dufour, S Amina, V Martinez-Cerdeno - Parkinsonism & related …, 2021 - Elsevier
Abstract Introduction Fragile X Tremor and Ataxia Syndrome is a progressive
neurodegenerative disorder that develops in some FMR1 premutation carriers. The …
neurodegenerative disorder that develops in some FMR1 premutation carriers. The …
Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a single genetic
mutation in the Fmr1 gene, serving as the largest genetic cause of intellectual disability …
mutation in the Fmr1 gene, serving as the largest genetic cause of intellectual disability …
[HTML][HTML] FMR1 is identified as an immune-related novel prognostic biomarker for renal clear cell carcinoma: A bioinformatics analysis of TAZ/YAP
S Wu, H He, J Huang, S Jiang, X Deng… - Mathematical …, 2022 - aimspress.com
WW domain-containing transcription regulator 1 (TAZ, or WWTR1) and Yes-associated
protein 1 (YAP) are both important effectors of the Hippo pathway and exhibit different …
protein 1 (YAP) are both important effectors of the Hippo pathway and exhibit different …
Fragile X mental retardation protein‐regulated proinflammatory cytokine expression in the spinal cord contributes to the pathogenesis of inflammatory pain induced by …
Y Yang, J Zhao, Y Li, X Li, X Chen… - Journal of …, 2021 - Wiley Online Library
Studies have verified that Fragile X mental retardation protein (FMRP), an RNA‐binding
protein, plays a potential role in the pathogenesis of formalin‐and (RS)‐3, 5 …
protein, plays a potential role in the pathogenesis of formalin‐and (RS)‐3, 5 …
[HTML][HTML] Altered inflammatory response in FMRP-deficient microglia
JM Parrott, T Oster, HY Lee - Iscience, 2021 - cell.com
Fragile X syndrome (FXS) is an inherited intellectual disability with a high risk for comorbid
autism spectrum disorders. Since FXS is a genetic disease, patients are more susceptible to …
autism spectrum disorders. Since FXS is a genetic disease, patients are more susceptible to …