Glycosylation of small molecules like specialized (secondary) metabolites has a profound
impact on their solubility, stability or bioactivity, making glycosides attractive compounds as …

Oligosaccharides and polysaccharides constitute the principal components of
carbohydrates, which are important biomacromolecules that demonstrate considerable …

The functionalization of glycosides with ionic compounds such as ionic liquids provides
enhanced polarity for the labelled glycans thanks to the presence of a permanent positive …

Oligosaccharides, in either free or bound forms, play crucial roles in a wide range of
biological processes. Increasing appreciation of their roles in cellular communication …

Lysosomal accumulation of the glycosphingolipid globotriaosylceramide Gb3 is linked to the
deficient activity of the α-galactosidase A in the Anderson–Fabry disease and an elevated …

The human cell surface trisaccharide motifs globotriose and P1 antigen play key roles in
infections by pathogenic bacteria, which makes them important synthetic targets as …

Galactokinase, the enzyme which catalyses the first committed step in the Leloir pathway,
has attracted interest due to its potential as a biocatalyst and as a possible drug target in the …

Abstract Globotriose (Galα1–4Galβ1–4Glc) is an important cell surface epitope that acts as
the receptor for Shiga-like toxins, and it is also the core structure of Globo H and SSEA4 that …

Galactose is ubiquitous. The synthesis of galactose‐containing oligosaccharides using
Leloir galactosyltransferase requires uridine diphosphate (UDP)‐galactose as the precursor …

Directed evolution of an α-galactosidase (Aga2) from Bifidobacterium breve 203 by random
mutagenesis and subsequently by site-directed mutagenesis provided a mutant enzyme …