Review of potential health risks associated with nanoscopic calcium phosphate

M Epple - Acta biomaterialia, 2018 - Elsevier
Calcium phosphate is applied in many products in biomedicine, but also in toothpastes and
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …

Nanoparticle–protein interactions: therapeutic approaches and supramolecular chemistry

M Kopp, S Kollenda, M Epple - Accounts of chemical research, 2017 - ACS Publications
Conspectus Research on nanoparticles has evolved into a major topic in chemistry.
Concerning biomedical research, nanoparticles have decisively entered the field, creating …

Illuminating Platinum Transportation while Maximizing Therapeutic Efficacy by Gold Nanoclusters via Simultaneous Near-Infrared-I/II Imaging and Glutathione …

Y Yang, Y Yu, H Chen, X Meng, W Ma, M Yu, Z Li… - ACS …, 2020 - ACS Publications
Killing tumor cells with a visualized system is a promising strategy in tumor therapy to
achieve minimal side effects and high efficiency. Herein, a theranostic nanomedicine …

Self-targeting visualizable hyaluronate nanogel for synchronized intracellular release of doxorubicin and cisplatin in combating multidrug-resistant breast cancer

W Ma, Q Chen, W Xu, M Yu, Y Yang, B Zou, YS Zhang… - Nano Research, 2021 - Springer
Multidrug-resistance (MDR) featuring complicated and poorly defined mechanisms is a
major obstacle to the success of cancer chemotherapy in the clinic. Compound …

Breaking the intracellular redox balance with diselenium nanoparticles for maximizing chemotherapy efficacy on patient-derived xenograft models

D Wei, Y Yu, X Zhang, Y Wang, H Chen, Y Zhao… - ACS …, 2020 - ACS Publications
Excessive oxidative stress in cancer cells can induce cancer cell death. Anticancer activity
and drug resistance of chemotherapy are closely related to the redox state of tumor cells …

A systematic strategy of combinational blow for overcoming cascade drug resistance via NIR‐light‐triggered hyperthermia

L Wang, Y Yu, D Wei, L Zhang, X Zhang… - Advanced …, 2021 - Wiley Online Library
A systematic combination strategy is proposed for overcoming cisplatin resistance using
near‐infrared (NIR)‐light‐triggered hyperthermia. A new photothermal polymer DAP‐F is …

The Future of Layer-by-Layer Assembly: A Tribute to ACS Nano Associate Editor Helmuth Möhwald

S Zhao, F Caruso, L Dähne, G Decher, BG De Geest… - ACS …, 2019 - ACS Publications
Layer-by-layer (LbL) assembly is a widely used tool for engineering materials and coatings.
In this Perspective, dedicated to the memory of ACS Nano associate editor Prof. Dr. Helmuth …

Silver nanoparticles with different size and shape: equal cytotoxicity, but different antibacterial effects

J Helmlinger, C Sengstock, C Groß-Heitfeld, C Mayer… - RSC …, 2016 - pubs.rsc.org
The influence of silver nanoparticle morphology on the dissolution kinetics in ultrapure water
as well as the biological effect on eukaryotic and prokaryotic cells was examined. Silver …

The origin of heterogeneous nanoparticle uptake by cells

P Rees, JW Wills, MR Brown, CM Barnes… - Nature …, 2019 - nature.com
Understanding nanoparticle uptake by biological cells is fundamentally important to wide-
ranging fields from nanotoxicology to drug delivery. It is now accepted that the arrival of …

NIR-II light evokes DNA cross-linking for chemotherapy and immunogenic cell death

Y Huang, D Wei, B Wang, D Tang, A Cheng, S Xiao… - Acta Biomaterialia, 2023 - Elsevier
As a DNA damaging agent, oxaliplatin (OXA) can induce immunogenic cell death (ICD) in
tumors to activate the immune system. However, the DNA damage induced by OXA is limited …