[HTML][HTML] A role for correlated spontaneous activity in the assembly of neural circuits
Before the onset of sensory transduction, developing neural circuits spontaneously generate
correlated activity in distinct spatial and temporal patterns. During this period of patterned …
correlated activity in distinct spatial and temporal patterns. During this period of patterned …
International union of basic and clinical pharmacology. CI. Structures and small molecule modulators of mammalian adenylyl cyclases
Adenylyl cyclases (ACs) generate the second messenger cAMP from ATP. Mammalian cells
express nine transmembrane AC (mAC) isoforms (AC1–9) and a soluble AC (sAC, also …
express nine transmembrane AC (mAC) isoforms (AC1–9) and a soluble AC (sAC, also …
Connecting the retina to the brain
The visual system is beautifully crafted to transmit information of the external world to visual
processing and cognitive centers in the brain. For visual information to be relayed to the …
processing and cognitive centers in the brain. For visual information to be relayed to the …
Developmental mechanisms of topographic map formation and alignment
J Cang, DA Feldheim - Annual review of neuroscience, 2013 - annualreviews.org
Brain connections are organized into topographic maps that are precisely aligned both
within and across modalities. This alignment facilitates coherent integration of different …
within and across modalities. This alignment facilitates coherent integration of different …
Visual circuit development requires patterned activity mediated by retinal acetylcholine receptors
The elaboration of nascent synaptic connections into highly ordered neural circuits is an
integral feature of the developing vertebrate nervous system. In sensory systems, patterned …
integral feature of the developing vertebrate nervous system. In sensory systems, patterned …
[HTML][HTML] Muscarinic M1 receptors modulate working memory performance and activity via KCNQ potassium channels in the primate prefrontal cortex
Working memory relies on the dorsolateral prefrontal cortex (dlPFC), where microcircuits of
pyramidal neurons enable persistent firing in the absence of sensory input, maintaining …
pyramidal neurons enable persistent firing in the absence of sensory input, maintaining …
Organization of the dorsal lateral geniculate nucleus in the mouse
D Kerschensteiner, W Guido - Visual neuroscience, 2017 - cambridge.org
The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the principal conduit for
visual information from retina to visual cortex. Viewed initially as a simple relay, recent …
visual information from retina to visual cortex. Viewed initially as a simple relay, recent …
Visual cortex gains independence from peripheral drive before eye opening
Visual spatial perception in the mammalian brain occurs through two parallel pathways: one
reaches the primary visual cortex (V1) through the thalamus and another the superior …
reaches the primary visual cortex (V1) through the thalamus and another the superior …
A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors
The development of neuronal circuits is controlled by guidance molecules that are
hypothesized to interact with the cholesterol-enriched domains of the plasma membrane …
hypothesized to interact with the cholesterol-enriched domains of the plasma membrane …
Activity dependent mechanisms of visual map formation-From retinal waves to molecular regulators
The refinement of neural connections requires activity-dependent mechanisms in addition to
the genetic program initially establishing wiring diagrams. The well-understood organization …
the genetic program initially establishing wiring diagrams. The well-understood organization …