Non‐coding RNAs: regulators of disease

RJ Taft, KC Pang, TR Mercer, M Dinger… - The Journal of …, 2010 - Wiley Online Library
For 50 years the term 'gene'has been synonymous with regions of the genome encoding
mRNAs that are translated into protein. However, recent genome‐wide studies have shown …

The role of exportin-5 in microRNA biogenesis and cancer

K Wu, J He, W Pu, Y Peng - Genomics, Proteomics and …, 2018 - academic.oup.com
MicroRNAs (miRNAs) are conserved small non-coding RNAs that play an important role in
the regulation of gene expression and participate in a variety of biological processes. The …

Genome‐wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

J Gong, Y Tong, HM Zhang, K Wang, T Hu… - Human …, 2012 - Wiley Online Library
MicroRNAs (miRNAs) are studied as key regulators of gene expression involved in different
diseases. Several single nucleotide polymorphisms (SNPs) in miRNA genes or target sites …

The role of microRNAs in human diseases

KU Tüfekci, MG Öner, RLJ Meuwissen… - … : MicroRNA biology and …, 2014 - Springer
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now
microRNAs are implicated in a variety of physiological and pathological processes. Since …

Population differences in microRNA expression and biological implications

RS Huang, ER Gamazon, D Ziliak, Y Wen, HK Im… - RNA biology, 2011 - Taylor & Francis
Population differences observed for complex traits may be attributed to the combined effect
of socioeconomic, environmental, genetic and epigenetic factors. To better understand …

[HTML][HTML] MicroRNA, nutrition, and cancer prevention

SA Ross, CD Davis - Advances in nutrition, 2011 - Elsevier
MicroRNA (miRNA) are small noncoding RNA molecules that are involved in post-
transcriptional gene silencing. Alterations in miRNA expression are observed in and may …

Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders

E Maffioletti, D Tardito, M Gennarelli… - Frontiers in cellular …, 2014 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNAs (20–22 nucleotides) playing a major role
in post-transcriptional regulation of gene expression. miRNAs are predicted to regulate more …

The impact of chromosomal rearrangements on regulation of gene expression

L Harewood, P Fraser - Human molecular genetics, 2014 - academic.oup.com
The effects that coding region single-nucleotide polymorphisms or mutations have on gene
expression have been well documented, predominantly owing to their association with …

Novel modulators of senescence, aging, and longevity: Small non-coding RNAs enter the stage

J Grillari, R Grillari-Voglauer - Experimental gerontology, 2010 - Elsevier
During the last decade evidence has accumulated that the aging process is driven by limited
allocation of energy to somatic maintenance resulting in accumulation of stochastic damage …

Integrating microRNAs into a system biology approach to acute lung injury

T Zhou, JGN Garcia, W Zhang - Translational Research, 2011 - Elsevier
Acute lung injury (ALI), including the ventilator-induced lung injury (VILI) and the more
severe acute respiratory distress syndrome (ARDS), are common and complex inflammatory …