Introduction White matter hyperintensities (WMH) are often described in Alzheimer's disease
(AD), but their topography and specific relationships with cognition remain unclear. Methods …

Background White matter hyperintensities (WMH) are very frequent in older adults and
associated with worse cognitive performance. Little is known about the links between WMH …

The term vascular cognitive disorder (VCD) refers to a heterogeneous group of disorders in
which the primary feature is cognitive impairment attributable to cerebrovascular disease …

White matter hyperintensities (WMHs) are commonly assumed to represent non-specific
cerebrovascular disease comorbid to neurodegenerative processes, rather than playing a …

Introduction Impact of white matter hyperintensities (WMH) on cognition likely depends on
lesion location, but a comprehensive map of strategic locations is lacking. We aimed to …

White matter hyperintensities (WMH) are generally considered to be associated with
cerebral small vessel disease, especially, in older age. Although significant sex differences …

White matter hyperintensities (WMH) are commonly detected in the brain of elderly
individuals and have been associated with a negative impact on multiple cognitive domains …

Background Lesions of cerebral small vessel disease, such as white matter hyperintensities
(WMHs) in individuals with cardiometabolic risk factors, interfere with the trajectories of the …

Frontal lobe structures decline faster than most other brain regions in older adults. Age-
related change in the frontal lobe is associated with poorer executive function (eg, working …

The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is
among the main causes of cognitive decline. We investigated the relation between white …