A Landscape of Methodology and Implementation of Adaptive Designs in Cancer Clinical Trials
YY Zhu, WX Wang, SK Cheuk, GR Feng, XG Li… - Critical Reviews in …, 2024 - Elsevier
Background The use of adaptive designs in cancer trials has considerably increased
worldwide in recent years, along with the release of various guidelines for their application …
worldwide in recent years, along with the release of various guidelines for their application …
Continued cancer drug approvals in Japan and Europe after market withdrawal in the United States: A comparative study of accelerated approvals
Regulatory authorities must balance ensuring evidence of efficacy and safety of new drugs.
Various regulatory pathways, such as the accelerated approval program in the United States …
Various regulatory pathways, such as the accelerated approval program in the United States …