Tandem repeats represent one of the most abundant class of variations in human genomes,
which are polymorphic by nature and become highly unstable in a length-dependent …

Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is
within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of …

Established as one of the world's most widely read gynecology texts, Clinical Gynecologic
Endocrinology and Infertility is now in its Seventh Edition. In a clear, user-friendly style …

Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

Premature ovarian failure (POF) causing hypergonadotrophic hypogonadism occurs in 1%
of women. In majority of cases the underlying cause is not identified. The known causes …

Infertility is an important issue for patients with premature ovarian failure (POF). Although
oocyte donation offers an alternative method to achieve a pregnancy, many patients seek to …

Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a disorder of
infertility characterized by amenorrhoea, low estrogen levels and increased gonadotropin …

The full mutation leading to the fragile X syndrome is a dynamic trinucleotide repeat located
in the 5′ untranslated region of the FMR1 gene. The premutation allele contains …

Carriers of premutation alleles (55–200 CGG repeats) of the fragile-X mental retardation 1
(FMR1) gene are often regarded as being clinically uninvolved. However, it is now apparent …

OBJECTIVE: To update clinicians on the reproductive implications of premutations in FMR1
(fragile X mental retardation 1). Fragile X syndrome, a cause of mental retardation and …