Hypermobile Ehlers–Danlos syndrome (aka Ehlers–Danlos syndrome Type III and Ehlers–Danlos syndrome hypermobility type): Clinical description and natural …

B Tinkle, M Castori, B Berglund… - American Journal of …, 2017 - Wiley Online Library
The hypermobile type of Ehlers–Danlos syndrome (hEDS) is likely the most common
hereditary disorder of connective tissue. It has been described largely in those with …

Chronic constipation

M Camilleri, AC Ford, GM Mawe, PG Dinning… - Nature reviews Disease …, 2017 - nature.com
Chronic constipation is a prevalent condition that severely impacts the quality of life of those
affected. Several types of primary chronic constipation, which show substantial overlap …

Hypermobile Ehlers‐Danlos syndromes: Complex phenotypes, challenging diagnoses, and poorly understood causes

C Gensemer, R Burks, S Kautz, DP Judge… - Developmental …, 2021 - Wiley Online Library
Abstract The Ehlers‐Danlos syndromes (EDS) are a group of heritable, connective tissue
disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility …

Ehlers–Danlos syndrome, classical type

JM Bowen, GJ Sobey, NP Burrows… - American Journal of …, 2017 - Wiley Online Library
Classical EDS is a heritable disorder of connective tissue. Patients are affected with joint
hypermobility, skin hyperextensibilty, and skin fragility leading to atrophic scarring and …

Irritable bowel syndrome: treatment based on pathophysiology and biomarkers

M Camilleri, G Boeckxstaens - Gut, 2023 - gut.bmj.com
Objective To appraise the evidence that pathophysiological mechanisms and individualised
treatment directed at those mechanisms provide an alternative approach to the treatment of …

Gastrointestinal involvement in the Ehlers–Danlos syndromes

A Fikree, G Chelimsky, H Collins… - American Journal of …, 2017 - Wiley Online Library
Current evidence suggests that an association exists between non‐inflammatory hereditary
disorders of connective tissue such as the Ehlers–Danlos syndromes (EDS) and …

Hypermobile Ehlers–Danlos syndrome and disorders of the gastrointestinal tract: What the gastroenterologist needs to know

PA Thwaites, PR Gibson… - … of Gastroenterology and …, 2022 - Wiley Online Library
Abstract Background and Aim Hypermobile Ehlers–Danlos syndrome (hEDS) and the
hypermobility spectrum disorders (HSD) can be challenging to diagnose and manage …

Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and …

SM Scott, M Simrén, AD Farmer… - …, 2021 - Wiley Online Library
ABSTRACT BACKGROUND Chronic constipation is a prevalent disorder that affects
patients' quality of life and consumes resources in healthcare systems worldwide. In clinical …

A review of respiratory manifestations and their management in Ehlers-Danlos syndromes and hypermobility spectrum disorders

K Chohan, N Mittal, L McGillis… - Chronic Respiratory …, 2021 - journals.sagepub.com
Background: Ehlers-Danlos Syndromes (EDS) and Hypermobility Spectrum Disorders
(HSD) are a heterogeneous group of heritable genetic connective tissue disorders with …

Updates on the psychological and psychiatric aspects of the Ehlers–Danlos syndromes and hypermobility spectrum disorders

A Bulbena‐Cabré, C Baeza‐Velasco… - American Journal of …, 2021 - Wiley Online Library
The field of the psychiatric and psychological aspects of Ehlers–Danlos syndromes (EDS)
has been understudied and neglected for many years. People with EDS are often classified …