Cell signaling, the essential role of O-GlcNAc!

NE Zachara, GW Hart - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2006 - Elsevier
An increasing body of evidence points to a central regulatory role for glucose in mediating
cellular processes and expands the role of glucose well beyond its traditional role (s) in …

Leptin effects on pancreatic β-cell gene expression and function

J Seufert - Diabetes, 2004 - Am Diabetes Assoc
The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate
with adipose tissue mass. Leptin was first described to act on the satiety center in the …

Plasma leptin and exercise: recent findings

MW Hulver, JA Houmard - Sports medicine, 2003 - Springer
It is established that plasma leptin is associated with satiety and that leptin stimulates lipid
metabolism, and increases energy expenditure. These effects implicate leptin as a major …

Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes …

S Marshall - Science's STKE, 2006 - science.org
Traditionally, nutrients such as glucose and amino acids have been viewed as substrates for
the generation of high-energy molecules and as precursors for the biosynthesis of …

Sexual dimorphism and regulation of resistin, adiponectin, and leptin expression in the mouse

Y Gui, JV Silha, LJ Murphy - Obesity Research, 2004 - Wiley Online Library
Objective: To examine gender differences and hormonal regulation of resistin, adiponectin,
and leptin. Research Methods and Procedures: Plasma levels were measured, and mRNA …

[HTML][HTML] Insulinorresistencia e hiperinsulinemia como factores de riesgo para enfermedad cardiovascular

J Rojas, V Bermúdez, E Leal, R Cano, Y Luti… - … de Farmacología y …, 2008 - ve.scielo.org
La Insulinoresistencia se define como un estado metabólico en el cual los efectos
periféricos titulares de la insulina se encuentran disminuidos. La resistencia a la acción de …

Leptin receptors are developmentally regulated in rat pituitary and hypothalamus

BA Morash, A Imran, D Wilkinson, E Ur… - Molecular and cellular …, 2003 - Elsevier
We have previously reported that leptin is expressed in adult rat brain and pituitary gland,
though the role of leptin in these sites has not been determined. Leptin mRNA is …

Appearance of leptin in wound fluid as a response to injury

M Marikovsky, CI Rosenblum, Z Faltin… - Wound repair and …, 2002 - Wiley Online Library
The adiposity hormone leptin regulates food intake, body weight, reproduction and other
metabolic and endocrine functions mainly through signaling to the hypothalamus. Leptin …

In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation

AD Zimmerman, RBS Harris - American Journal of …, 2015 - journals.physiology.org
We previously reported that a 2-day peripheral infusion of glucosamine caused leptin
resistance in rats, suggesting a role for the hexosamine biosynthetic pathway (HBP) in the …

[PDF][PDF] ROLE OF LEPTIN IN THE CONTROL OF POSTPRANDIAL PANCREATIC

J Jaworek, J Bonior, SJ Konturek, J Bilski… - Journal of physiology …, 2003 - jpp.krakow.pl
Leptin released by adipocytes has been implicated in the control of food intake but recent
detection of specific leptin receptors in the pancreas suggests that this peptide may also play …