Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

Abstract Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin
(NGAL), is a secreted glycoprotein that belongs to a group of transporters of small lipophilic …

Abstract Lipocalin 2 (Lcn2), as an antimicrobial peptide is expressed in intestine, and the
upregulation of intestinal Lcn2 has been linked to inflammatory bowel disease. However, the …

Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …

Objective Adipose tissue is the largest endocrine organ. When activated by cancer cells,
adipocytes secrete adipocytokines and release fatty acids, which are then transferred to …

Lipocalin 2 (Lcn2) has been previously characterized as an adipokine/cytokine and
implicated in obesity and inflammation. Herein, we investigated the role and potential …

Lipocalin 2 (Lcn2) has been recently characterized as a new adipokine having a role in
innate immunity and energy metabolism. Nonetheless, the metabolic regulation of Lcn2 …

BACKGROUND: The present study was aimed at isolating an antidiabetic molecule from a
herbal source and assessing its mechanism of action. METHODS: Embelin, isolated from …