To investigate the association of gene polymorphisms of TNF‑α‑308G/A rs1800629 with the
susceptibility and severity of rheumatoid arthritis (RA), literature from PubMed, EMBASE …

Genetic investigations of rheumatoid arthritis have predominantly been single nucleotide
polymorphism-based candidate gene association studies searching for markers of …

OBJECTIVE: Tumor necrosis factor-alpha (TNF-alpha) promoter-308 A/G polymorphism has
been reported to be associated with rheumatoid arthritis (RA) with inconsistent results. We …

Rheumatoid arthritis (RA) is a model of multigenic inflammatory disorder in which tumor
necrosis factor-α (TNF-α) plays an important role. Genetic factors may be implicated in the …

Aim of the work To evaluate the clinical significance of serum levels of tumor necrosis factor
alpha (TNFα) and-308 G/A promoter polymorphism in rheumatoid arthritis (RA) patients …

Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are autoimmune, inflammatory
diseases with substantial genetic contributions. Matrix metalloproteinase (MMP)-2, tumor …

Rheumatoid arthritis (RA) is a chronic autoimmune disorder associated with altered
expression of pro-inflammatory cytokines. We aim to elucidate the association between the …

The objective was to analyze the possible involvement of tumour necrosis factor‐alpha (TNF‐
α)− 308 G/A promoter polymorphism in the susceptibility and/or the disease profile of …

In this study we analyzed whether the polymorphisms 676T> G in the tumor necrosis factor
receptor (TNFR) II gene and− 308G> A in the TNFα promoter gene may influence the …

The aim of this study was to determine whether the tumor necrosis factor-α (TNF-α) promoter–
308 A/G polymorphism is associated with susceptibility to rheumatoid arthritis (RA) in …