Wheat is a major cereal crop providing energy and nutrients to the billions of people around
the world. Gluten is a structural protein in wheat, that is necessary for its dough making …

Immunoglobulin A (IgA) is the most abundant antibody class present at mucosal surfaces.
The production of IgA exceeds the production of all other antibodies combined, supporting …

Purpose Although genetic predisposition and exposure to dietary gluten are considered
necessary triggers for the development of coeliac disease, alterations in the gut microbial …

The microbiome plays an important role in maintaining human health. Despite multiple
factors being attributed to the shaping of the human microbiome, extrinsic factors such diet …

Current treatment for celiac disease (CD) is adhering to a gluten-free diet (GFD), although its
long-term molecular effects are still undescribed. New molecular features detectable in stool …

Celiac disease (CD) is a chronic inflammatory enteropathy caused by gluten (protein from
wheat, rye and, barley) in genetically predisposed individuals carrying the HLA-DQ2/HLA …

For decades, the pathogenesis of a variety of human diseases has been attributed to
increased intestinal paracellular permeability even though scientific evidence supporting …

Recurrent oral ulcerations are manifestations of a heterogeneous set of both general and
more‐or‐less specific oral diseases due to numerous potential etiologies, including, but not …

Intestinal epithelial cells (IECs) constitute the border between the vast antigen load present
in the intestinal lumen and the mucosal immune compartment. Their ability to express …

Background Celiac disease is a chronic autoimmune disease triggered by gluten exposure
in genetically predisposed individuals. A life-long intake of a gluten-free (GF) diet is required …