[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates

M Careaga, T Murai, MD Bauman - Biological psychiatry, 2017 - Elsevier
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …

Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model

AC Kentner, SD Bilbo, AS Brown, EY Hsiao… - …, 2019 - nature.com
Abstract The 2017 American College of Neuropychopharmacology (ACNP) conference
hosted a Study Group on 4 December 2017, Establishing best practice guidelines to …

A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude

A Saghazadeh, B Ataeinia, K Keynejad… - Journal of psychiatric …, 2019 - Elsevier
Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …

Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia

FL Haddad, SV Patel, S Schmid - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Profiling inflammatory signatures of schizophrenia: a cross-sectional and meta-analysis study

D Frydecka, M Krzystek-Korpacka, A Lubeiro… - Brain, behavior, and …, 2018 - Elsevier
We aimed to profile a broad panel of inflammatory markers in patients with schizophrenia
and healthy controls. Additionally, we performed a meta-analysis of chemokine alterations …

Maternal immune activation in neurodevelopmental disorders

CM Solek, N Farooqi, M Verly, TK Lim… - Developmental …, 2018 - Wiley Online Library
Converging lines of evidence from basic science and clinical studies suggest a relationship
between maternal immune activation (MIA) and neurodevelopmental disorders such as …

Sex differences in the effect of maternal immune activation on cognitive and psychosis‐like behaviour in Long Evans rats

A Gogos, A Sbisa, D Witkamp… - European Journal of …, 2020 - Wiley Online Library
Maternal immune activation during pregnancy is associated with increased risk of
development of schizophrenia in later life. There are sex differences in schizophrenia …

Effects of stress on behavioral flexibility in rodents

JL Hurtubise, JG Howland - Neuroscience, 2017 - Elsevier
Cognitive flexibility is the ability to switch between different rules or concepts and behavioral
flexibility is the overt physical manifestation of these shifts. Behavioral flexibility is essential …

Poly (I: C) source, molecular weight and endotoxin contamination affect dam and prenatal outcomes, implications for models of maternal immune activation

HM Kowash, HG Potter, ME Edye, EP Prinssen… - Brain, behavior, and …, 2019 - Elsevier
The viral mimetic polyinosinic: polycytidylic acid (poly (I: C)) is increasingly used to induce
maternal immune activation (mIA) to model neurodevelopmental disorders (NDDs). Robust …