Appropriate mitochondrial physiology is an essential for health and survival. Cells have
developed unique mechanisms to adapt to stress circumstances and changes in metabolic …

Accumulation of dysfunctional and damaged cellular proteins and organelles occurs during
aging, resulting in a disruption of cellular homeostasis and progressive degeneration and …

Polyphenols, ubiquitously present in fruits and vegetables, have been traditionally viewed
as antioxidant molecules. Such contention emerged, mainly from their well established in …

In addition to oxidative phosphorylation (OXPHOS), mitochondria perform other functions
such as heme biosynthesis and oxygen sensing and mediate calcium homeostasis, cell …

Succinate dehydrogenase, which is known as mitochondrial complex II, has proven to be a
fascinating machinery, attracting renewed and increased interest in its involvement in …

Mitochondria are essential organelles for cellular integrity and functionality maintenance
and their imparement is implicated in the development of a wide range of diseases …

A Mediterranean diet rich in olive oil has profound influence on health outcomes including
metabolic syndrome. However, the active compound and detailed mechanisms still remain …

Abstract Background Olive (Olea europaea L.) oil is one of the main ingredients of the
Mediterranean diets and as such, it is considered responsible for the overall well being of …

The tight coordination between mitochondrial biogenesis and mitophagy can be
dysregulated during aging, critically influencing whole-body metabolism, health, and …

Obesity is a health problem worldwide, and energy imbalance has been pointed out as one
of the main factors responsible for its development. As mitochondria are a key element in …