Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

Targeting inflammatory mediators: an anticancer mechanism of thymoquinone action

Z Akter, FR Ahmed, M Tania… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Thymoquinone is a promising anticancer molecule, the chemopreventive role
of which is well-known at least in vitro and in the animal model. In this review article, we …

Photothermal therapeutic potency of plasmonic silver nanoparticles for apoptosis and anti-angiogenesis in testosterone induced benign prostate hyperplasia in rats

BH Marghani, A Fehaid, AI Ateya, MA Ezz, RM Saleh - Life Sciences, 2022 - Elsevier
Aims In this study, we used a near-infrared laser (NIR) to increase the potency of silver
nanoparticles (AgNPs) to develop a novel, less invasive, and simple photothermal therapy …

Effect of gold nanoparticles treatment on the testosterone-induced benign prostatic hyperplasia in rats

B Al-Trad, A Aljabali, M Al Zoubi… - International journal of …, 2019 - Taylor & Francis
Background: Gold nanoparticles (AuNps) are promising agents for prostate cancer therapy.
Herein, the in vivo effects of 20 and 50 nm sized AuNps on experimentally induced benign …

Resistance exercise‐induced increase in muscle 5α‐dihydrotestosterone contributes to the activation of muscle Akt/mTOR/p70S6K‐and Akt/AS160/GLUT4‐signaling …

N Horii, N Hasegawa, S Fujie, M Uchida… - The FASEB …, 2020 - Wiley Online Library
Abstract Effects of increase in muscle 5α‐dihydrotestosterone (DHT) levels caused by
resistance exercise on regulation of mammalian target of rapamycin (mTOR)‐and glucose …

The angiotensin converting enzyme inhibitor captopril attenuates testosterone-induced benign prostatic hyperplasia in rats; a mechanistic approach

F Mostafa, EM Mantawy, SS Azab… - European Journal of …, 2019 - Elsevier
Benign prostatic hyperplasia (BPH) is the most widespread urological disorder among
elderly men. It is influenced by several factors, among which is the prostatic renin …

Chemical profiles of the active fraction from Prinsepia utilis Royle leaves and its anti-benign prostatic hyperplasia evaluation in animal models

Y Peng, C Peng, Y Wu, C Sun, X Li - BMC Complementary Medicine and …, 2021 - Springer
Abstract Background The Prinsepia utilis Royle leaves (P. utilis) is a folk herb used for
benign prostatic hyperplasia (BPH) control by ethnic minorities for centuries in China with …

Role of PPAR‐α agonist fenofibrate in the treatment of induced benign prostatic hyperplasia with dysplastic changes in rats

MMM Refaie, RA Rifaai… - Fundamental & Clinical …, 2018 - Wiley Online Library
Nearly all men who reach average life expectancy have prostate disease. The most common
is benign prostatic hyperplasia (BPH). Peroxisome proliferator‐activated receptor alpha …

Chemopreventive Efficacy of Thymoquinone in Chemically Induced Urinary Bladder Carcinogenesis in Rat

KS Hamaamin, BH Marouf - BioMed Research International, 2022 - Wiley Online Library
The effects of thymoquinone (TQ) in a carcinogen‐based models of urinary bladder cancer
were evaluated, using 45 male rats in five groups. In negative control (n= 10), only tap water …

[PDF][PDF] Efficacy and Safety of Thymoquinone on Suppression of Tumor Growth in N-butyl-N-(4-hydroxybutyl)-Nitrosamine-Induced Bladder Cancer in Rats

KSH Qadir, BH Marouf - Iraqi Journal of Pharmaceutical Sciences (P-ISSN …, 2023 - iasj.net
Bladder cancer is one of the most common genitourinary malignancies worldwide, the
therapeutic approaches for suppression of urothelial tumor and progression toward distant …