Living, working and exercising in extreme terrestrial environments are challenging tasks
even for healthy humans of the modern new age. The issue is not just survival in remote …

Introduction Perinatal asphyxia (PA) still causes significant morbidity and mortality.
Therapeutic hypothermia (TH) is the only effective therapy for neonates with moderate to …

Purpose To compare the time-course changes in DNA methylation and mRNA expression
for selected myogenic regulatory factors (MYOD1, MYF5, and MYF6) immediately post-, 4 …

At low temperatures, the liver increases glucose utilization and expresses RNA-binding motif
3 (RBM3) to cope with cold exposure. In this study, the expression of heat shock protein 70 …

Proteins secreted from skeletal muscle serving a signalling role have been termed
myokines. Many of the myokines are exercise factors, produced and released in response to …

The study aimed to determine whether combining cryostimulation with resistance training
would effectively increase muscle strength, and if so, whether this adaptation would be …

The utilisation of synthetic torpor for interplanetary travel once seemed farfetched. However,
mounting evidence points to torpor-induced protective benefits from the main hazards of …

Peroxisome proliferator-activated receptor-α coactivator-1α (PGC-1α) mRNA is increased
with both exercise and exposure to cold temperature. However, transcriptional control has …

Cold exposure during cycling and recovery enhances PGC-1α transcription, but aspects of
mitophagy and a more intense cold exposure without recovery occurring in the cold have not …

Purpose In the present study, the effects of endurance exercise under different
environmental temperatures on myokine responses were elucidated. Methods Seven …