The Cyclin-dependent kinase (CDK) class of serine/threonine kinases has crucial roles in
the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers …

Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …

Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …

MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that have been
found highly conserved among species. MiRNAs are able to negatively regulate gene …

Abstract Hsa-miRNA-206 (miR-206), highly expressed in skeletal muscle, has recently been
discovered to have anticancer properties in different tissues. However, the role of miR-206 …

Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(Malat1) functions as an oncogene in many types of human cancer. In this study, we show …

Background MicroRNAs play important roles in the pathogenesis of various kinds of tumors.
However, there are few studies on the expression profile and function of miRNAs in …

Melanoma is the utmost fatal kind of skin neoplasms. Molecular changes occurring during
the pathogenic processes of initiation and progression of melanoma are diverse and include …

Non-coding RNAs play a crucial role in maintaining genomic stability which is essential for
cell survival and preventing tumorigenesis. Through an extensive crosstalk between non …