Human ascariasis: diagnostics update

PHL Lamberton, PM Jourdan - Current tropical medicine reports, 2015 - Springer
Soil-transmitted helminths (STHs) infect over one billion people worldwide. Ascariasis may
mimic a number of conditions, and individual clinical diagnosis often requires a thorough …

IgE cross‐reactivity between Ascaris lumbricoides and mite allergens: possible influences on allergic sensitization and asthma

N Acevedo, L Caraballo - Parasite immunology, 2011 - Wiley Online Library
Nematode infections such as Ascariasis are important health problems in underdeveloped
countries, most of them located in the tropics where environmental conditions also promote …

Evidence for a peak shift in a humoral response to helminths: age profiles of IgE in the Shuar of Ecuador, the Tsimane of Bolivia, and the US NHANES

AD Blackwell, MD Gurven, LS Sugiyama… - PLoS neglected …, 2011 - journals.plos.org
Background The peak shift model predicts that the age-profile of a pathogen's prevalence
depends upon its transmission rate, peaking earlier in populations with higher transmission …

Co-infection with Ascaris lumbricoides modulates protective immune responses against Giardia duodenalis in school Venezuelan rural children

I Hagel, M Cabrera, F Puccio, C Santaella, E Buvat… - Acta tropica, 2011 - Elsevier
We evaluated the effect of Ascaris lumbricoides on Giardia duodenalis infection and
TH1/TH2 type immune mechanisms toward this parasite in 251 rural parasitized and 70 …

Ascaris lumbricoides: an overview of therapeutic targets

I Hagel, T Giusti - … -Drug Targets (Formerly Current Drug Targets …, 2010 - ingentaconnect.com
A. lumbricoides is the largest of the common nematode parasites of man and has been
associated with intestinal pathology, respiratory symptoms and malnutrition in children from …

Association between total immunoglobulin E and antibody responses to naturally acquired Ascaris lumbricoides infection and polymorphisms of immune system …

N Acevedo, D Mercado, C Vergara… - Clinical & …, 2009 - academic.oup.com
Summary The 13q33–34 region harbours a susceptibility locus to Ascaris lumbricoides,
although the underlying genes are unknown. Immunoglobulin (Ig) E and IgG confer …

Immune serum–activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae

G Coakley, B Volpe, T Bouchery, K Shah… - Parasite …, 2020 - Wiley Online Library
Helminth infection represents a major health problem causing approximately 5 million
disability‐adjusted life years worldwide. Concerns that repeated anti‐helminthic treatment …

IgG4 autoantibodies and autoantigens in the context of IgG4-autoimmune disease and IgG4-related disease

RV Motta, EL Culver - Frontiers in Immunology, 2024 - frontiersin.org
Immunoglobulins are an essential part of the humoral immune response. IgG4 antibodies
are the least prevalent subclass and have unique structural and functional properties. In this …

Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for monitoring of human ascariasis in endemic settings

RM Mugo, S Rausch, ZD Musimbi… - PLOS Neglected …, 2024 - journals.plos.org
Background The standard diagnosis of Ascaris lumbricoides and other soil-transmitted
helminth (STH) infections relies on the detection of worm eggs by copromicroscopy …

Spontaneous cytokine production in children according to biological characteristics and environmental exposures

CA Figueiredo, NM Alcântara-Neves… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Environmental factors are likely to have profound effects on the development of
host immune responses, with serious implications for infectious diseases and inflammatory …