A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

The human gut microbiome plays an important role in resisting colonization of the host by
pathogens, but we lack the ability to predict which communities will be protective. We …

Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …

Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Increasing experimental evidence suggests that administering live commensal bacterial
species can optimize microbiome composition and lead to reduced disease severity and …

Colonization of the gastrointestinal (GI) tract by Klebsiella pneumoniae is generally
considered asymptomatic. However, gut colonization allows K. pneumoniae to either …

Bacterial genome editing commonly relies on chromosomal cleavage with Cas nucleases to
counter-select against unedited cells. However, editing normally requires efficient …

Hepatocellular carcinoma (HCC) is accompanied by an altered gut microbiota but whether
the latter contributes to carcinogenesis is unclear. Here we show that faecal microbiota …

Nonalcoholic fatty liver disease (NAFLD) is associated with high carbohydrate (HC) intake.
We investigated whether the relationship between carbohydrate intake and NAFLD is …