Expanding drug resistance could become a major problem in malaria treatment, as only a
limited number of effective antimalarials are available. Drug resistance has been associated …

Abstract Heat shock protein 90 (Hsp90) is essential for the development of the main malaria
agent, Plasmodium falciparum. Inhibitors that target Hsp90 function are known to not only kill …

Piscirickettsia salmonis is a fish bacterial pathogen that has severely challenged the
sustainability of the Chilean salmon industry since its appearance in 1989. As this Gram …

The Clp chaperones and proteases play an important role in protein homeostasis in the cell.
They are highly conserved across prokaryotes and found also in the mitochondria of …

Background The spread of drug resistance has been a major obstacle to the control of
malaria. The mechanisms underlying drug resistance in malaria seem to be complex and …

The dynamic chromatin landscape displaying combinatorial complexity of the epigenome
impacts gene expression that underlies many events of differentiation and cell cycle …

Background Leishmania virulence factors responsible for the complicated epidemiology of
the various leishmaniases remain mainly unidentified. This study is a characterization of a …

Velvet (VeA), a light-regulated protein that shuttles between the cytoplasm and the nucleus,
serves as a key global regulator of secondary metabolism in various Aspergillus species …

Cyclin-dependent kinases (CDKs) have an established role in metazoans and yeast in DNA
replication, transcription and cell cycle regulation. Several CDKs and their effectors have …

More than sesquicentennial years of malarial research, however the unique malarial
parasite, Plasmodium still bewilders us with its atypical characteristic features. Elimination …