Laboratory diagnosis of melioidosis: past, present and future

SKP Lau, S Sridhar, CC Ho, WN Chow… - Experimental …, 2015 - journals.sagepub.com
Melioidosis is an emerging, potentially fatal disease caused by Burkholderia pseudomallei,
which requires prolonged antibiotic treatment to prevent disease relapse. However …

Melioidosis: clinical impact and public health threat in the tropics

R Perumal Samy, BG Stiles, G Sethi… - PLoS neglected tropical …, 2017 - journals.plos.org
This review briefly summarizes the geographical distribution and clinical impact of
melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative …

[HTML][HTML] A review of melioidosis cases in the Americas

TJ Benoit, DD Blaney, TJ Doker, JE Gee… - The American journal …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a bacterial infection caused by Burkholderia pseudomallei, a gram-negative
saprophytic bacillus. Cases occur sporadically in the Americas with an increasing number of …

Farnesol increases the susceptibility of Burkholderia pseudomallei biofilm to antimicrobials used to treat melioidosis

D Castelo‐Branco, GB Riello… - Journal of applied …, 2016 - academic.oup.com
Aims The aim of this study was to analyse the in vitro activity of farnesol alone and combined
with the antibacterial drugs amoxicillin, doxycycline, ceftazidime and sulfamethoxazole …

Rapid and Sensitive Multiplex Detection of Burkholderia pseudomallei-Specific Antibodies in Melioidosis Patients Based on a Protein Microarray Approach

C Kohler, SJ Dunachie, E Müller, A Kohler… - PLoS neglected …, 2016 - journals.plos.org
Background The environmental bacterium Burkholderia pseudomallei causes the infectious
disease melioidosis with a high case-fatality rate in tropical and subtropical regions. Direct …

PCR-based Methodologies Used to Detect and Differentiate the Burkholderia pseudomallei complex: B. pseudomallei, B. mallei, and B. thailandensis

W Lowe, JK March, AJ Bunnell, KL O'Neill… - Current issues in …, 2014 - mdpi.com
Methods for the rapid detection and differentiation of the Burkholderia pseudomallei
complex comprising B. pseudomallei, B. mallei, and B. thailandensis, have been the topic of …

Melioidosis in South America

DB Rolim, RXR Lima, AKC Ribeiro… - Tropical medicine and …, 2018 - mdpi.com
Melioidosis is an emerging disease in the Americas. This paper reviews confirmed cases,
the presence of Burkholderia pseudomallei and the organization of national surveillance …

Comparative Burkholderia pseudomallei natural history virulence studies using an aerosol murine model of infection

S Massey, LA Yeager, CA Blumentritt, S Vijayakumar… - Scientific reports, 2014 - nature.com
Melioidosis is an endemic disease caused by the bacterium Burkholderia pseudomallei.
Concerns exist regarding B. pseudomallei use as a potential bio-threat agent causing …

A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B …

CW Lowe, BA Satterfield, DB Nelson, JD Thiriot… - PLoS …, 2016 - journals.plos.org
The Burkholderia pseudomallei complex classically consisted of B. mallei, B. pseudomallei,
and B. thailandensis, but has now expanded to include B. oklahomensis, B …

Factors affecting clinical outcomes in the management of melioidosis in Singapore: a 16-year case series

JMF Chien, SE Saffari, AL Tan, TT Tan - BMC infectious diseases, 2018 - Springer
Background Burkholderia pseudomallei is a gram negative bacteria that causes a spectrum
of human diseases in the tropics. Although melioidosis is endemic in Southeast Asia, large …