The COVID-19 pandemic is an extraordinary global emergency that has led to the
implementation of unprecedented measures in order to stem the spread of the infection …

Vitamin D deficiency is a common health problem worldwide, in particular among older
people. Vitamin D regulates and modulates the physiology and function of multiple human …

Protein-energy wasting (PEW), a term proposed by the International Society of Renal
Nutrition and Metabolism (ISRNM), refers to the multiple nutritional and catabolic alterations …

The hormonal metabolite of vitamin D, 1α, 25-dihydroxyvitamin D 3 (1, 25D), initiates
biological responses via binding to the vitamin D receptor (VDR). When occupied by 1, 25D …

As bones are levers for skeletal muscle to exert forces, both are complementary and
essential for locomotion and individual autonomy. In the past decades, the idea of a bone …

Beyond its established role in bone and mineral homeostasis, there is emerging evidence
that vitamin D exerts a range of effects in skeletal muscle. Reports of profound muscle …

Muscle strength plays an important role in determining risk for falls, which result in fractures
and other injuries. While bone loss has long been recognized as an inevitable consequence …

Sarcopenia and osteoporosis have recently been noted for their relationship with locomotive
syndrome and increased number of older people. Sarcopenia is defined by decreased …

This review discusses the clinical and laboratory studies that have examined a role of
vitamin D in skeletal muscle. Many observational studies, mainly in older populations …

Context: Studies examining whether vitamin D supplementation increases muscle mass or
muscle-specific vitamin D receptor (VDR) concentration are lacking. Objective: Our objective …