The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

Chronic kidney disease (CKD) in patients with diabetes mellitus (DM) is a major problem of
public health. Currently, many of these patients experience progression of cardiovascular …

In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

Glucagon-like peptide-1 (GLP-1), an incretin hormone secreted primarily from the intestinal
L-cells in response to meals, modulates nutrient homeostasis via actions exerted in multiple …

Aims/hypothesis Glucagon-like peptide-1 (GLP-1) lowers glucose levels by potentiating
glucose-induced insulin secretion and inhibiting glucagon release. The question of whether …

We investigated a possible role of the central glucagon-like peptide (GLP-1) receptor system
as an essential brain circuit regulating adiposity through effects on nutrient partitioning and …

Bariatric surgery is currently the most effective treatment for obesity. Not only do these types
of surgeries produce significant weight loss but also they improve insulin sensitivity and …

Glucagon-like peptide 1 (GLP-1) functions as an incretin hormone with antidiabetogenic
properties. However, the role of GLP-1 in human bone marrow-derived mesenchymal stem …

BACKGROUND & AIMS: Bariatric surgery has been shown to reverse type 2 diabetes;
however, mechanisms by which this occurs remain undefined. Ileal interposition (IT) is a …