Microvesicles and exosomes: new players in metabolic and cardiovascular disease
C Lawson, JM Vicencio, DM Yellon… - Journal of …, 2016 - joe.bioscientifica.com
The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …
referring to extracellular vesicles (EVs). For many years considered to be extracellular …
[HTML][HTML] Adipose tissue in control of metabolism
L Luo, M Liu - Journal of endocrinology, 2016 - joe.bioscientifica.com
Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …
homeostasis through its subtle functions at both organ and systemic levels. On one hand …
SGLT-2 inhibitors and GLP-1 receptor agonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. A consensus …
Chronic kidney disease (CKD) in patients with diabetes mellitus (DM) is a major problem of
public health. Currently, many of these patients experience progression of cardiovascular …
public health. Currently, many of these patients experience progression of cardiovascular …
Regulation of adipocyte lipolysis
G Frühbeck, L Méndez-Giménez… - Nutrition research …, 2014 - cambridge.org
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
Glucagon-like peptide-1: glucose homeostasis and beyond
YM Cho, Y Fujita, TJ Kieffer - Annual review of physiology, 2014 - annualreviews.org
Glucagon-like peptide-1 (GLP-1), an incretin hormone secreted primarily from the intestinal
L-cells in response to meals, modulates nutrient homeostasis via actions exerted in multiple …
L-cells in response to meals, modulates nutrient homeostasis via actions exerted in multiple …
Direct effect of GLP-1 infusion on endogenous glucose production in humans
M Seghieri, E Rebelos, A Gastaldelli, BD Astiarraga… - Diabetologia, 2013 - Springer
Aims/hypothesis Glucagon-like peptide-1 (GLP-1) lowers glucose levels by potentiating
glucose-induced insulin secretion and inhibiting glucagon release. The question of whether …
glucose-induced insulin secretion and inhibiting glucagon release. The question of whether …
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity
R Nogueiras, D Pérez-Tilve… - Journal of …, 2009 - Soc Neuroscience
We investigated a possible role of the central glucagon-like peptide (GLP-1) receptor system
as an essential brain circuit regulating adiposity through effects on nutrient partitioning and …
as an essential brain circuit regulating adiposity through effects on nutrient partitioning and …
Does bariatric surgery improve adipose tissue function?
Bariatric surgery is currently the most effective treatment for obesity. Not only do these types
of surgeries produce significant weight loss but also they improve insulin sensitivity and …
of surgeries produce significant weight loss but also they improve insulin sensitivity and …
Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow
C Sanz, P Vazquez, C Blazquez… - American Journal …, 2010 - journals.physiology.org
Glucagon-like peptide 1 (GLP-1) functions as an incretin hormone with antidiabetogenic
properties. However, the role of GLP-1 in human bone marrow-derived mesenchymal stem …
properties. However, the role of GLP-1 in human bone marrow-derived mesenchymal stem …
Ileal interposition surgery improves glucose and lipid metabolism and delays diabetes onset in the UCD-T2DM rat
BP Cummings, AD Strader, KL Stanhope, JL Graham… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Bariatric surgery has been shown to reverse type 2 diabetes;
however, mechanisms by which this occurs remain undefined. Ileal interposition (IT) is a …
however, mechanisms by which this occurs remain undefined. Ileal interposition (IT) is a …