Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

In some diseases, a very important role is played by the ability of bacteria to form multi-
dimensional complex structure known as biofilm. The most common disease of the oral …

The pneumococcus is the classic Gram-positive extracellular pathogen. The medical burden
of diseases it causes is amongst the greatest in the world. Intense study for more than 100 …

Streptococcus pneumoniae (pneumococcus) is a major cause of worldwide mortality and
morbidity, and to a large extent is vaccine-preventable. Nasopharyngeal carriage of …

Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …

Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …

Most commensal and pathogenic bacteria interacting with eukaryotic hosts express
adhesive molecules on their surfaces that promote interaction with host cell receptors or with …

In Gram‐positive bacteria proteins are displayed on the cell surface using sortase enzymes.
These cysteine transpeptidases join proteins bearing an appropriate sorting signal to …

Streptococcus pneumoniae is a major pathogen of humans, causing diseases such as
pneumonia and meningitis. The organism produces several virulence factors that are …

Background Streptococcus pneumoniae is one of the most important causes of microbial
diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed …